Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032929 | 0.76 | — | — | |
| SCHEMBL28826612 | 0.72 | KDM4E (0.34) | KDM4EPKMTHRBCA2PTGS1 | |
| SCHEMBL23366826 | 0.69 | KDM4E (0.35) | KDM4EEPHX1 | |
| SCHEMBL23366825 | 0.67 | TDP1 (0.33) | KDM4ECRBN | |
| SCHEMBL31617030 | 0.67 | PKM (0.38) | KDM4EPKMTHRBCA2PTGS1 | |
| SCHEMBL7129495 | 0.65 | — | — | |
| SCHEMBL7128936 | 0.63 | — | — | |
| SCHEMBL24820865 | 0.63 | POLB (0.34) | KDM4EPKMTHRBCA2PTGS1 | |
| SCHEMBL124179 | 0.63 | — | — | |
| SCHEMBL27265453 | 0.63 | EPHX1 (0.42) | KDM4EPKMTHRBCA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684843-B1 | TECHNETIUM-99m LABELED PEPTIDES FOR DIAGNOSTIC IMAGING OF INFLAMMATION | DIATIDE INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-0684843-B1 | TECHNETIUM-99m LABELED PEPTIDES FOR DIAGNOSTIC IMAGING OF INFLAMMATION | DIATIDE INC (US) | 2006-05-10 | — | — | EP | disclosed |
| US-6107459-A | REAGENT WHICH BINDS TO SITES OF INFECTION, INFLAMMATION, THROMBOSIS, ATHEROSCLEROSIS AND NEOPLASTIC GROWTH IN VIVO | DIATIDE, INC. (US) | 2000-08-22 | — | — | US | disclosed |