Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LCLAT1 | Q6UWP7 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569245 | 0.92 | KMT2A (0.41) | MAPTHPGDTSHRHSD17B10POLB | |
| SCHEMBL570416 | 0.87 | ALDH1A1 (0.37) | MAPTHPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL569330 | 0.83 | MAPK8 (0.42) | MAPTHPGDTSHRHSD17B10POLB | |
| SCHEMBL570488 | 0.81 | NPC1 (0.50) | MAPTHPGDPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL569407 | 0.78 | LCLAT1 (0.45) | MAPTLCLAT1HCRTR1TP53LMNA | |
| SCHEMBL569756 | 0.77 | DRD3 (0.54) | MAPTHPGDHSD17B10LCLAT1POLB | |
| SCHEMBL10183288 | 0.77 | LCLAT1 (0.45) | MAPTLCLAT1HCRTR1TP53KDM4E | |
| SCHEMBL569786 | 0.76 | HCAR2 (0.48) | MAPTHPGDHSD17B10POLBALDH1A1 | |
| SCHEMBL569400 | 0.75 | HTT (0.38) | MAPTHPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL569396 | 0.75 | ALDH1A1 (0.38) | MAPTHPGDHSD17B10POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |