Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 15/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694184 | 0.78 | HTR4 (0.60) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| Piboserod SCHEMBL467339 | 0.77 | HTR4 (1.00) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| Piboserod SCHEMBL30234609 | 0.77 | HTR4 (1.00) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| Piboserod SCHEMBL2228911 | 0.76 | HTR4 (0.98) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| SCHEMBL5806105 | 0.72 | HTR4 (0.73) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| SCHEMBL8575502 | 0.70 | HTR4 (0.53) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| SCHEMBL6909544 | 0.70 | HTR4 (1.00) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| SCHEMBL1077431 | 0.68 | HTR4 (0.50) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| SCHEMBL7326328 | 0.68 | HTR4 (0.64) | HTR4CHRM2ADRA2BHRH2HTR1D | |
| SCHEMBL8286732 | 0.68 | HTR4 (1.00) | HTR4CHRM2ADRA2BHRH2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476136-B1 | PHARMACEUTICAL COMPOSITION COMPRISING N-((1-N-BUTYL-4-PIPERIDINYL)MENTHYL)-3,4-DIHYDRO-2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE OR SALT AND PROCESS FOR PREPARING THEREOF COMPRISING DRY GRANULATION | GLAXO GROUP LTD (GB) | 2006-06-14 | — | — | EP | disclosed |
| EP-1476136-A1 | PHARMACEUTICAL COMPOSITION COMPRISING N-((1-N-BUTYL-4-PIPERIDINYL)MENTHYL)-3,4-DIHYDRO-2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE OR SALT AND PROCESS THEREFOR COMPRISING DRY GRANULATION | GLAXO GROUP LIMITED (GB) | 2004-11-17 | — | — | EP | disclosed |