Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484026 | 0.84 | SRD5A1 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL949200 | 0.82 | NOTUM (0.38) | ALDH1A1TSHRLMNASRD5A1 | |
| SCHEMBL8484091 | 0.81 | NOTUM (0.38) | CA12CA9ALDH1A1PTGS2LMNA | |
| SCHEMBL8483611 | 0.81 | HDAC3 (0.32) | ALDH1A1MAOBMAOATBXAS1SRD5A1 | |
| SCHEMBL5694225 | 0.80 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27322660 | 0.78 | TBXAS1 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8484097 | 0.77 | CYP11B1 (0.46) | PTGS2DRD2 | |
| SCHEMBL346265 | 0.77 | CYP11B1 (0.51) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL5694168 | 0.76 | ESR2 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL983738 | 0.76 | MAOA (0.49) | ALDH1A1ALOX5TSHRMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342770-B1 | Polymerizable liquid crystal compound, liquid crystal polymer and applications thereof | FUJI PHOTO FILM CO LTD (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-1342770-A1 | Polymerizable liquid crystal compound, liquid crystal polymer and applications thereof | FUJI PHOTO FILM CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-0284359-B1 | 1,4-DISUBSTITUTED PIPERAZINE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4880809-A | HYPOTENSIVE AGENTS, AMIDE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| CN-88101588-A | Preparation 1, the method for 4-disubstituted piperazines compounds | — | 1988-11-23 | — | — | CN | disclosed |
| EP-0284359-A1 | 1,4-Disubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |