SCHEMBL5694485

SCHEMBL5694485

O=C(O)Cc1cc2c(C(=O)O)cccc2[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.45
KDM4E B2RXH2 5/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 2/20 0.44
HPGD P15428 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 2/20 0.44
GAA P10253 2/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
EGFR P00533 2/20 0.42
PARP1 P09874 1/20 0.42
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
GRIN2D O15399 2/20 0.40
GRIN3B O60391 2/20 0.40
GRIN1 Q05586 2/20 0.40
GRIN2A Q12879 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7425591 0.85 RHEB (0.47) PBRM1KDM4EALDH1A1MEN1HPGD
SCHEMBL19644194 0.84 PBRM1 (0.45) PBRM1KDM4EALDH1A1MAPTMEN1
SCHEMBL9534359 0.82 KDM4E (0.46) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL8724326 0.81 HMGB1 (0.46) PBRM1KDM4EALDH1A1MEN1HPGD
SCHEMBL28577623 0.81 FLT3 (0.45) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL30468720 0.81 DAO (0.51) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL28589699 0.81 DAO (0.51) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL1439650 0.81 DAO (0.51) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL10824679 0.81 KDM4E (0.44) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL2648755 0.78 KDM4E (0.41) KDM4EALDH1A1MAPTMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539492-B1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2006-05-17 EP disclosed
EP-1539492-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES Kodak Polychrome Graphics, LLC (US) 2005-06-15 EP disclosed
US-6899992-B2 Polymerizable compounds with quadruple hydrogen bond forming groups KODAK POLYCHROME GRAPHICS LLC (US) 2005-05-31 US disclosed
US-6893797-B2 High speed negative-working thermal printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2005-05-17 US disclosed
WO-2004043935-A1 POLYMERIZABLE COMPOUNDS WITH QUADRUPLE HYDROGEN BOND FORMING GROUPS KODAK POLYCHROME GRAPHICS LLC (US) 2004-05-27 WO disclosed
US-20040091812-A1 Polymerizable compounds with quadruple hydrogen bond forming groups KODAK AMERICAS LTD. 2004-05-13 US disclosed
WO-2004014652-A1 HIGH SPEED NEGATIVE-WORKING THERMAL PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2004-02-19 WO disclosed
US-20030124460-A1 High speed negative-working thermal printing plates KODAK PHILIPPINES LTD. 2003-07-03 US disclosed
EP-0068563-A2 Heterocyclic acetic acid compounds and compositions for treating bone diseases THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 EP disclosed