SCHEMBL1439650

SCHEMBL1439650

O=C(O)Cc1cc2c(Cl)cccc2[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.51
AKR1B1 P15121 1/20 0.49
FLT3 P36888 2/20 0.45
HRH4 Q9H3N8 1/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GPR17 Q13304 1/20 0.43
RHEB Q15382 1/20 0.43
GAA P10253 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30468720 1.00 DAO (0.51) DAOAKR1B1FLT3HRH4KDM4E
SCHEMBL9534359 0.82 KDM4E (0.46) DAOAKR1B1HRH4KDM4EALDH1A1
SCHEMBL152992 0.82 MTNR1A (0.47) DAOFLT3HRH4KDM4EALDH1A1
SCHEMBL28577623 0.81 FLT3 (0.45) FLT3HRH4KDM4EALDH1A1MAPT
SCHEMBL10824679 0.81 KDM4E (0.44) AKR1B1KDM4EALDH1A1MAPTMEN1
SCHEMBL5694485 0.81 PBRM1 (0.45) KDM4EALDH1A1MAPTMEN1HPGD
SCHEMBL28589699 0.81 DAO (0.51) DAOFLT3KDM4EALDH1A1MAPT
SCHEMBL4561870 0.80 RHEB (0.57) DAOFLT3HRH4RHEB
SCHEMBL4979042 0.79 DAO (0.51) DAOFLT3HRH4RHEB
SCHEMBL2648755 0.78 KDM4E (0.41) AKR1B1KDM4EALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194483-A1 BIOLOGICAL METHOD FOR DECARBOXYLATION OF CANNABINOIDS DIRECTLY IN PLANT TISSUES ALKION BIOINNOVATIONS (FR) 2025-06-19 US claimed
EP-4492967-A1 BIOLOGICAL METHOD FOR DECARBOXYLATION OF CANNABINOIDS DIRECTLY IN PLANT TISSUES Alkion Bioinnovations (FR) 2025-01-22 EP claimed
WO-2023175125-A1 BIOLOGICAL METHOD FOR DECARBOXYLATION OF CANNABINOIDS DIRECTLY IN PLANT TISSUES ALKION BIOINNOVATIONS (FR) 2023-09-21 WO claimed
WO-2017144065-A1 SUSTAINABLE AND INDUSTRIAL PRODUCTION OF GUAIANOLIDES BASED ON ORGAN TISSUE CULTURE UNIVERSITY OF COPENHAGEN (DK) 2017-08-31 WO claimed
US-8404930-B2 Methods for improving monocot transformation PIONEER HI-BRED INTERNATIONAL, INC. (US) 2013-03-26 US claimed
US-8361929-B2 Method of restoring male sterility in gramineous plants and male sterility restorative agent TOHOKU UNIVERSITY (JP) 2013-01-29 US claimed
US-20100215625-A1 EFFICIENT PREPARATION OF NAPHTHOQUINONE ANTICANCER ACTIVE INGREDIENTS TAHEEBO JAPAN CO., LTD. (JP) 2010-08-26 US claimed
US-20100192253-A1 METHODS FOR IMPROVING MONOCOT TRANSFORMATION PIONEER HI-BRED, INC. (US) 2010-07-29 US claimed
WO-2010040990-A2 PRODUCTION OF COMPOUNDS FROM PLANTS ST. GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2010-04-15 WO claimed
US-7442549-B2 Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid SAPPORO BREWERIES LIMITED (JP) 2008-10-28 US claimed
WO-2006027865-A2 METHOD OF TRANSFORMING CHLOROPLAST OF COMPOSITE PLANT RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH (JP) 2006-03-16 WO claimed
US-20050289663-A1 Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid SAPPORO BREWERIES LIMITED (JP) 2005-12-29 US claimed
EP-1541015-A1 METHOD OF CONSTRUCTING ORCHID HAPLOID BY TREATING UNFERTILIZED OCRHID FLOWER WITH AUXIN AND METHOD OF GROWING ORCHID Sapporo Breweries Limited (JP) 2005-06-15 EP claimed
EP-1005651-A1 METHODS OF IDENTIFYING BIOLOGICAL AGENT COMPOSITIONS SUPRATEK PHARMA, INC. (CA) 2000-06-07 EP claimed
WO-1999008112-A1 METHODS OF IDENTIFYING BIOLOGICAL AGENT COMPOSITIONS SUPRATEK PHARMA INC. (CA) 1999-02-18 WO claimed
JP-7184496-A None JP disclosed
EP-4197318-B1 PHOSPHODIESTERASES INHIBITORS TO PROMOTE IN VITRO PLANT CELL REPROGRAMMING TOWARDS PLANT EMBRYOGENESIS OR MICROCALLUS FORMATION UNIV FREIBURG ALBERT LUDWIGS (DE) 2025-11-19 EP disclosed
WO-1998056334-A1 COMPOSITIONS FOR DELIVERY OF BIOLOGICAL AGENTS AND METHODS FOR THE PREPARATION THEREOF UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 1998-12-17 WO disclosed
WO-1998056348-A1 COMPOSITIONS FOR DELIVERY OF BIOLOGICAL AGENTS AND METHODS FOR THE PREPARATION THEREOF UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) 1998-12-17 WO disclosed
JP-H07184496-A CALLUS GROWTH MEDIUM NISSAN CHEM IND LTD 1995-07-25 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100215625-A1 EFFICIENT PREPARATION OF NAPHTHOQUINONE ANTICANCER ACTIVE INGREDIENTS NDUFB10, NQO2, NDUFA10 DAO 3803/4885AKR1B1 908/4885FLT3 3559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.