Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425591 | 0.83 | RHEB (0.47) | PBRM1MTNR1AMTNR1BPARP1KDM4E | |
| SCHEMBL19644194 | 0.81 | PBRM1 (0.45) | PBRM1MTNR1AMTNR1BPARP1KDM4E | |
| SCHEMBL5694485 | 0.81 | PBRM1 (0.45) | PBRM1MTNR1AMTNR1BPARP1KDM4E | |
| SCHEMBL10983500 | 0.80 | CTSV (0.59) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10978966 | 0.80 | CTSV (0.59) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10978475 | 0.80 | CTSV (0.59) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30120739 | 0.78 | HTR2C (0.45) | MTNR1AMTNR1BHTR7HTR6CCNK | |
| SCHEMBL17557251 | 0.76 | GFER (0.38) | PBRM1MTNR1AMTNR1BPARP1KDM4E | |
| SCHEMBL11810213 | 0.74 | DAO (0.46) | MTNR1AMTNR1BHTR7HTR6CYP1A2 | |
| SCHEMBL29721596 | 0.74 | KDM4E (0.59) | PBRM1PARP1KDM4EALDH1A1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780498-A | PEPTIDE DERIVATIVES FOR CARDIOVASCULAR AND BRAIN DISORDERS | CIBA-GEIGY JAPAN LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |