Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968132 | 1.00 | MAPT (0.59) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL968131 | 1.00 | MAPT (0.59) | MAPTLMNAGAANR1I2PGR | |
| Hydrochloric Acid SCHEMBL7020610 | 0.98 | MAPT (0.58) | MAPTLMNAGAANR1I2PGR | |
| Hydrochloric Acid SCHEMBL3135048 | 0.98 | MAPT (0.58) | MAPTLMNAGAANR1I2PGR | |
| Hydrogen Sulfide SCHEMBL28193705 | 0.98 | MAPT (0.58) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL3737087 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL8120449 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL3929244 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL19236061 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL9982497 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321606-B | Preparation method of ceftizoxime sodium and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-112321606-A | Preparation method of ceftizoxime sodium and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-110903303-A | Preparation method of cefepime hydrochloride compound | 山东金城柯瑞化学有限公司 | 2020-03-24 | — | — | CN | claimed |
| WO-2005100369-A1 | DEPLETION OF E-ISOMERS IN PREPARATION OF Z-ENRICHED 3-(2-SUBSTITUTED VINYL) CEPHALOSPORINS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| WO-2024251301-A1 | GSPT1 PROTEIN DEGRADER CONTAINING OXIME STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080738-A | GSPT1 protein degradation agent containing oxime structure and preparation method and application thereof | 中国药科大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-112321606-B | Preparation method of ceftizoxime sodium and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112321606-B | Preparation method of ceftizoxime sodium and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112321606-A | Preparation method of ceftizoxime sodium and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-112321606-A | Preparation method of ceftizoxime sodium and intermediate thereof | 福安药业集团重庆博圣制药有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-110903303-A | Preparation method of cefepime hydrochloride compound | 山东金城柯瑞化学有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-110903303-A | Preparation method of cefepime hydrochloride compound | 山东金城柯瑞化学有限公司 | 2020-03-24 | — | — | CN | disclosed |
| US-4294960-A | 7-[2-(2-Aminothiazol-4-yl)-2-cyclopentyloxyiminoacetamido]-3-cephem-4-carboxylic acid (synisomer) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| EP-0002774-B1 | PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-23 | — | — | EP | disclosed |
| EP-0002765-B1 | CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| US-4279818-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4225707-A | 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-09-30 | — | — | US | disclosed |
| US-4166115-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| EP-0002765-A1 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |
| US-4152433-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-05-01 | — | — | US | disclosed |