SCHEMBL968131

SCHEMBL968131

CO/N=C(\C(=O)O)c1csc(N)n1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
LMNA P02545 2/20 0.59
GAA P10253 1/20 0.59
NR1I2 O75469 3/20 0.48
PGR P06401 1/20 0.48
PTGS2 P35354 1/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
ITGB1 P05556 2/20 0.47
ITGA4 P13612 2/20 0.47
HTR2C P28335 1/20 0.45
ALB P02768 1/20 0.43
PPARG P37231 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
SLC22A11 Q9NSA0 1/20 0.43
USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694533 1.00 MAPT (0.59) MAPTLMNAGAANR1I2PGR
SCHEMBL968132 1.00 MAPT (0.59) MAPTLMNAGAANR1I2PGR
Hydrochloric Acid SCHEMBL7020610 0.98 MAPT (0.58) MAPTLMNAGAANR1I2PGR
Hydrochloric Acid SCHEMBL3135048 0.98 MAPT (0.58) MAPTLMNAGAANR1I2PGR
Hydrogen Sulfide SCHEMBL28193705 0.98 MAPT (0.58) MAPTLMNAGAANR1I2PGR
SCHEMBL3737087 0.88 MAPT (0.48) MAPTLMNAGAANR1I2PGR
SCHEMBL8120449 0.88 MAPT (0.48) MAPTLMNAGAANR1I2PGR
SCHEMBL3929244 0.88 MAPT (0.48) MAPTLMNAGAANR1I2PGR
SCHEMBL19236061 0.88 MAPT (0.48) MAPTLMNAGAANR1I2PGR
SCHEMBL9982497 0.88 MAPT (0.48) MAPTLMNAGAANR1I2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110241406-B Preparation method of chemical gold-palladium-gold plating layer on plated PCB 深圳市溢诚电子科技有限公司 2021-10-08 CN claimed
CN-112321609-A Antibiotic improved cefmenoxime hydrochloride synthesis process 重庆化工职业学院 2021-02-05 CN claimed
EP-0533047-B1 Preparation of a cephalosporin antibiotic using the synisomer of a thiazolyl intermediate BRISTOL MYERS SQUIBB CO (US) 2003-05-07 EP claimed
WO-2002020819-A2 AN ENZYMATIC PROCESS FOR PREPARING β-LACTAM COMPOUNDS DSM N.V. (NL) 2002-03-14 WO claimed
EP-1186668-A1 An enzymatic process for preparing Beta-lactam compounds DSM N.V. (NL) 2002-03-13 EP claimed
US-20020006642-A1 METHOD FOR PREPARING A BETA-LACTAM ANTIBIOTIC DSM N.V. (NL) 2002-01-17 US claimed
EP-0531981-B1 Process for the preparation of a cephalosporin antibiotic BRISTOL MYERS SQUIBB CO (US) 2001-11-21 EP claimed
EP-1075479-A1 A METHOD FOR CRYSTALLIZING A BETA-LACTAM ANTIBIOTIC DSM N.V. (NL) 2001-02-14 EP claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0791597-A1 Method for manufacture of cephalosporins and intermediates thereof LUPIN LABORATORIES LIMITED (IN) 1997-08-27 EP claimed
US-5639877-A AMIDINE SALT OF 7-AMINO-3-HYDROXYMETHYL-3-CEPHEM-4-CARBOXYLIC ACID BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1997-06-17 US claimed
US-5502200-A Reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same LUCKY, LTD. (KR) 1996-03-26 US claimed
EP-0620228-A1 Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same LUCKY LTD. (KR) 1994-10-19 EP claimed
US-5159070-A Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid ROUSSEL UCLAF (FR) 1992-10-27 US claimed
EP-0091277-B1 DIMETHYLACETAMIDE SOLVATE OF SYN-(2-AMINO THIAZOL-4-YL)(METHOXYIMINO)ACETIC ACID ELI LILLY AND COMPANY (US) 1987-06-16 EP claimed
EP-0075600-B1 2-THIAZOLEAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-12-30 EP claimed
US-4426528-A Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid ELI LILLY AND COMPANY (US) 1984-01-17 US claimed
EP-0023453-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF 7-(2-ARYL)-2-HYDROXYIMINO-ACETAMIDO CEPHALOSPORANIC ACID ROUSSEL-UCLAF (FR) 1983-11-16 EP claimed
EP-0091277-A2 Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid ELI LILLY AND COMPANY (US) 1983-10-12 EP claimed