Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694533 | 1.00 | MAPT (0.59) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL968131 | 1.00 | MAPT (0.59) | MAPTLMNAGAANR1I2PGR | |
| Hydrochloric Acid SCHEMBL7020610 | 0.98 | MAPT (0.58) | MAPTLMNAGAANR1I2PGR | |
| Hydrochloric Acid SCHEMBL3135048 | 0.98 | MAPT (0.58) | MAPTLMNAGAANR1I2PGR | |
| Hydrogen Sulfide SCHEMBL28193705 | 0.98 | MAPT (0.58) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL3737087 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL8120449 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL3929244 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL19236061 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR | |
| SCHEMBL9982497 | 0.88 | MAPT (0.48) | MAPTLMNAGAANR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480105-B | Piperazine bridged naphthalimide aminothiazole oxime compound and preparation method and application thereof | 西南大学 | 2022-03-08 | — | — | CN | claimed |
| CN-112321609-A | Antibiotic improved cefmenoxime hydrochloride synthesis process | 重庆化工职业学院 | 2021-02-05 | — | — | CN | claimed |
| CN-102807573-B | Method for preparing ceftizoxime | SUZHOU ERYE PHARMACEUTICAL CO | 2014-04-16 | — | — | CN | claimed |
| CN-101830913-A | Cephalosporins parent nucleus derived compound, cephem onium salt compound prepared by same and method for preparing cephalosporins pyrazol sulfate by adopting same | YANTAI BAOHUA BIO TECHNOLOGY CO LTD | 2010-09-15 | — | — | CN | claimed |
| WO-2007004753-A1 | ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES | DONGBU HITEK CO., LTD. (KR) | 2007-01-11 | — | — | WO | claimed |
| US-7108996-B2 | Method for increasing luminescence assay sensitivity | PROMEGA CORPORATION (US) | 2006-09-19 | — | — | US | claimed |
| US-20060051827-A1 | Method for increasing luminescence assay sensitivity | PROMEGA CORPORATION | 2006-03-09 | — | — | US | claimed |
| WO-2005100369-A1 | DEPLETION OF E-ISOMERS IN PREPARATION OF Z-ENRICHED 3-(2-SUBSTITUTED VINYL) CEPHALOSPORINS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| US-6803461-B2 | CONDENSATION OF 7-AMINOCEPHALOSPORANIC ACID WITH FURYL-2-CARBONYLTHIOL IN BORONTRIFLUORIDE OR A COMPLEX, AND AN ORGANIC SOLVENT AT 0-50 DEGREES C. TO PRODUCE 7-AMINO-3-(2-(FURYLCARBONYL)THIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2004-10-12 | — | — | US | claimed |
| EP-0533047-B1 | Preparation of a cephalosporin antibiotic using the synisomer of a thiazolyl intermediate | BRISTOL MYERS SQUIBB CO (US) | 2003-05-07 | — | — | EP | claimed |
| EP-0673784-A2 | Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| EP-0587121-A1 | Crystalline dihydrate of a cephalosporin dihydrochloride salt and injectable compositions thereof | Bristol-Myers Squibb Company (US) | 1994-03-16 | — | — | EP | claimed |
| EP-0533047-A1 | Preparation of a cephalosporin antibiotic using the synisomer of a thiazolyl intermediate | Bristol-Myers Squibb Company (US) | 1993-03-24 | — | — | EP | claimed |
| EP-0531981-A1 | Process for the preparation of a cephalosporin antibiotic | Bristol-Myers Squibb Company (US) | 1993-03-17 | — | — | EP | claimed |
| US-5159070-A | Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid | ROUSSEL UCLAF (FR) | 1992-10-27 | — | — | US | claimed |
| EP-0091277-B1 | DIMETHYLACETAMIDE SOLVATE OF SYN-(2-AMINO THIAZOL-4-YL)(METHOXYIMINO)ACETIC ACID | ELI LILLY AND COMPANY (US) | 1987-06-16 | — | — | EP | claimed |
| EP-0075600-B1 | 2-THIAZOLEAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-12-30 | — | — | EP | claimed |
| US-4426528-A | Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | claimed |
| EP-0023453-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF 7-(2-ARYL)-2-HYDROXYIMINO-ACETAMIDO CEPHALOSPORANIC ACID | ROUSSEL-UCLAF (FR) | 1983-11-16 | — | — | EP | claimed |
| EP-0091277-A2 | Dimethylacetamide solvate of syn-(2-amino thiazol-4-yl)(methoxyimino)acetic acid | ELI LILLY AND COMPANY (US) | 1983-10-12 | — | — | EP | claimed |