Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109591 | 0.86 | MAPT (0.53) | MAPTNPSR1AKR1C3AKR1C2MEN1 | |
| SCHEMBL297769 | 0.76 | MAPT (0.60) | MAPTNPSR1MEN1KMT2AHPGD | |
| SCHEMBL31338514 | 0.76 | MAPT (0.60) | MAPTNPSR1MEN1KMT2AHPGD | |
| SCHEMBL16634718 | 0.74 | MAPT (0.56) | MAPTNPSR1MEN1KMT2AHPGD | |
| SCHEMBL16634720 | 0.74 | MAPT (0.56) | MAPTNPSR1MEN1KMT2AHPGD | |
| SCHEMBL1371283 | 0.73 | MAPT (0.57) | MAPTNPSR1HCAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL980549 | 0.72 | MAPT (0.78) | MAPTNPSR1KMT2AALDH3A1HCAR3 | |
| SCHEMBL980547 | 0.72 | MAPT (0.78) | MAPTNPSR1KMT2AALDH3A1HCAR3 | |
| Hydrochloric Acid SCHEMBL1890620 | 0.72 | MAPT (0.56) | MAPTNPSR1HCAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL10623543 | 0.70 | KMT2A (0.64) | MAPTAKR1C3AKR1C2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016148-A1 | PERMANENT HAIR COLORANTS BASED ON A CREAM-LIKE CARRIER AND A COMBINATION OF TRIS(HYDROXYMETHYL)AMINOMETHANE, AT LEAST AN AMINO ACID AND AN OXIDATIVE DYE | HCT - HAIR COSMETIC TECHNOLOGY AG (CH) | 2016-02-04 | — | — | WO | disclosed |
| EP-1660022-A2 | AGENT FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005032502-A2 | AGENT FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2005-04-14 | — | — | WO | disclosed |