Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694574 | 0.86 | MAPT (0.53) | MAPTNPSR1AKR1C3AKR1C2MEN1 | |
| SCHEMBL10531801 | 0.84 | MAPT (0.56) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL6135331 | 0.83 | MAPT (0.50) | MAPTNPSR1AKR1C3AKR1C2MEN1 | |
| SCHEMBL10531772 | 0.81 | L3MBTL1 (0.52) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL23567 | 0.81 | AKR1C3 (0.67) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL29785279 | 0.81 | AKR1C3 (0.67) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL29377063 | 0.81 | AKR1C3 (0.67) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL10530352 | 0.81 | AKR1C3 (0.71) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL27737633 | 0.77 | MAPT (0.45) | MAPTNPSR1AKR1C3AKR1C2MEN1 | |
| SCHEMBL297769 | 0.76 | MAPT (0.60) | MAPTNPSR1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6537328-B1 | Hair dye | L'OREAL S.A. (FR) | 2003-03-25 | — | — | US | claimed |
| EP-1047379-B1 | COMPOSITION FOR THE OXIDATIVE DYEING OF KERATINIC FIBERS COMPRISING A LACCASE AND DEYING PROCESS USING SUCH A COMPOSITION | OREAL (FR) | 2001-10-10 | — | — | EP | claimed |
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | claimed |
| US-11298304-B2 | Two component hair treatment kit comprising a hair coloring cream and a developer composition comprising a specific tensioactive compound | LABORATOIRE BIOSTHÉTIQUE KOSMETIK GMBH & CO. KG (DE) | 2022-04-12 | — | — | US | disclosed |
| US-20210128427-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | LABORATOIRE BIOSTHÉTIQUE KOSMETIK GMBH & CO. KG (DE) | 2021-05-06 | — | — | US | disclosed |
| EP-3773435-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | Laboratoire Biosthetique Kosmetik GmbH&Co. KG (DE) | 2021-02-17 | — | — | EP | disclosed |
| CN-111936110-A | Two-component hair treatment kit comprising a hair dye cream and a developer composition comprising specific surface-active compounds | 科斯梅蒂克生物技术实验室有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-106794127-B | Permanent hair dye based on an emulsion-like vehicle and a combination of tris (hydroxymethyl) aminomethane, at least one amino acid and an oxidation dye | HCT-头发化妆品技术股份公司 | 2020-05-29 | — | — | CN | disclosed |
| US-10456341-B2 | Compositions and methods for simultaneous reshaping and direct coloring of hair | ALFA PARF GROUP S.P.A. (IT) | 2019-10-29 | — | — | US | disclosed |
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | disclosed |
| WO-2019185127-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | HCT - HAIR COSMETIC TECHNOLOGY AG (CH) | 2019-10-03 | — | — | WO | disclosed |
| WO-1999002124-A2 | DIRECT HAIR DYE COMPOSITIONS AND METHODS CONTAINING NOVEL ANTHRAQUINONE MIXTURES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| EP-0891971-A1 | Bispyrazole-aza compounds, processes for their preparation, and hair dyeing agents containing these compounds | Wella Aktiengesellschaft (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0889719-A1 | AGENTS FOR DYING AND DECOLORIZING FIBERS | Wella Aktiengesellschaft (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0877593-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | Wella Aktiengesellschaft (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0867171-A2 | Powder composition for the preparation of gels comprising a methyl hydroxyalkyl cellulose | Wella Aktiengesellschaft (DE) | 1998-09-30 | — | — | EP | disclosed |
| WO-1998023247-A1 | AGENT FOR DYEING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998022078-A1 | AGENTS FOR DYING AND DECOLORIZING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-05-28 | — | — | WO | disclosed |
| EP-0578665-B1 | HAIR COLOURANTS WITH DIRECT DYES | HENKEL KGAA (DE) | 1994-12-21 | — | — | EP | disclosed |
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128427-A1 | TWO COMPONENT HAIR TREATMENT KIT COMPRISING A HAIR COLORING CREAM AND A DEVELOPER COMPOSITION COMPRISING A SPECIFIC TENSIOACTIVE COMPOUND | KRT18, KIT, PRKDC | MAPT 1857/4885NPSR1 3304/4885AKR1C3 37/4885 |
| US-11298304-B2 | Two component hair treatment kit comprising a hair coloring cream and a developer composition comprising a specific tensioactive compound | KRT18, KIT, PRKDC | MAPT 1857/4885NPSR1 3304/4885AKR1C3 37/4885 |
| US-10456341-B2 | Compositions and methods for simultaneous reshaping and direct coloring of hair | GRHPR, DAO, ALPG | MAPT 2959/4885NPSR1 3917/4885AKR1C3 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.