Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN9 | O14815 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695455 | 1.00 | CAPN9 (0.52) | CAPN9CASP3SNCACCNE1CDK2 | |
| SCHEMBL5695462 | 0.93 | ALDH1A1 (0.50) | CAPN9CASP3SNCAPTGS1PTGS2 | |
| SCHEMBL5695389 | 0.93 | ALDH1A1 (0.50) | CAPN9CASP3SNCAPTGS1PTGS2 | |
| SCHEMBL13080904 | 0.83 | RET (0.67) | SNCACCNE1CDK2NOX4MAPT | |
| SCHEMBL1851095 | 0.83 | RET (0.67) | SNCACCNE1CDK2NOX4MAPT | |
| SCHEMBL1851097 | 0.83 | RET (0.67) | SNCACCNE1CDK2NOX4MAPT | |
| SCHEMBL5695414 | 0.77 | MAPT (0.69) | SNCAMAPTAPPGSK3BCLK1 | |
| SCHEMBL5695417 | 0.77 | MAPT (0.69) | SNCAMAPTAPPGSK3BCLK1 | |
| SCHEMBL3503220 | 0.73 | MAPT (0.73) | CASP3MAPTAPPALDH1A1SMN1; SMN2 | |
| SCHEMBL13973920 | 0.73 | CAPN9 (0.58) | CAPN9CASP3SNCACCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300135-B1 | Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | claimed |
| EP-1300135-A1 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300135-B1 | Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | disclosed |
| EP-1300135-A1 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | disclosed |