Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | STK17B | O94768 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695413 | 1.00 | MAPT (0.60) | MAPTKMT2AMEN1HPGDHTT | |
| SCHEMBL5695458 | 0.88 | MAPT (0.64) | MAPTKMT2AMEN1HPGDHTT | |
| SCHEMBL5695419 | 0.88 | MAPT (0.64) | MAPTKMT2AMEN1HPGDHTT | |
| SCHEMBL5695414 | 0.82 | MAPT (0.69) | MAPTKMT2AMEN1HPGDHTT | |
| SCHEMBL10848654 | 0.82 | TYR (0.57) | MAPTKMT2AMEN1HPGDHTT | |
| SCHEMBL5695417 | 0.82 | MAPT (0.69) | MAPTKMT2AMEN1HPGDHTT | |
| SCHEMBL7843430 | 0.81 | ERBB2 (0.76) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5477780 | 0.81 | ERBB2 (0.76) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5477779 | 0.81 | ERBB2 (0.76) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10853940 | 0.81 | MAPT (0.89) | MAPTKMT2AMEN1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300135-B1 | Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | claimed |