Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849192 | 0.96 | TYR (0.56) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL153106 | 0.86 | MDM2 (0.54) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL153105 | 0.86 | MDM2 (0.54) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL19453394 | 0.84 | CGAS (0.59) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL5695413 | 0.82 | MAPT (0.60) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL5695423 | 0.82 | MAPT (0.60) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL10845785 | 0.79 | TYR (0.40) | TYRMAPTMEN1KMT2AMDM2 | |
| SCHEMBL5695458 | 0.79 | MAPT (0.64) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL5695419 | 0.79 | MAPT (0.64) | TYRMAPTMEN1KMT2AHPGD | |
| SCHEMBL5482740 | 0.77 | NPC1 (0.75) | MAPTMEN1KMT2AHPGDMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567048-A | SULFONATED INDOXYL DERIVATIVES | PFIZER INC. (US) | 1986-01-28 | — | — | US | disclosed |