Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 17/20 | 0.71 |
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD3 | P35462 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352001 | 1.00 | DRD4 (0.71) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL1877824 | 1.00 | DRD4 (0.71) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL13229950 | 0.91 | DRD4 (0.59) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL353574 | 0.89 | DRD4 (0.59) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL7371617 | 0.88 | DRD4 (0.76) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL21553759 | 0.86 | DRD4 (0.57) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL17803030 | 0.86 | DRD4 (0.57) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL735729 | 0.86 | DRD4 (0.73) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL2304936 | 0.86 | DRD4 (0.73) | DRD4DRD2DRD3CYP1A2CYP3A4 | |
| SCHEMBL5748888 | 0.86 | DRD4 (0.73) | DRD4DRD2DRD3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053923-B1 | TRIAZOLOPYRAZINE DERIVATIVES AS TYROSIN KINASE INHIBITORS | KOREA RES INST CHEMICAL TECH (KR) | 2018-04-11 | — | — | EP | disclosed |
| EP-3053923-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | Korea Research Institute of Chemical Technology (KR) | 2016-08-10 | — | — | EP | disclosed |
| US-9403831-B2 | Triazolopyrazine derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-08-02 | — | — | US | disclosed |
| US-9403831-B2 | Triazolopyrazine derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-08-02 | — | — | US | disclosed |
| US-9403831-B2 | Triazolopyrazine derivative and use thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-08-02 | — | — | US | disclosed |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | HANDOK INC. (KR) | 2015-09-17 | — | — | US | disclosed |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | HANDOK INC. (KR) | 2015-09-17 | — | — | US | disclosed |
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | HANDOK INC. (KR) | 2015-09-17 | — | — | US | disclosed |
| US-9079895-B2 | Morpholino compounds, uses and methods | UNIVERSITY OF DUNDEE (GB) | 2015-07-14 | — | — | US | disclosed |
| US-9079895-B2 | Morpholino compounds, uses and methods | UNIVERSITY OF DUNDEE (GB) | 2015-07-14 | — | — | US | disclosed |
| CN-1028527-C | Process for preparing coumarin derivatives | SANKYO CO (JP) | 1995-05-24 | — | — | CN | disclosed |
| EP-0411912-B1 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | SANKYO CO (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0589484-A1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0587194-A1 | 2-(Heterocycloalkoxy)-1-(subst.-phenyl)-ethanol derivatives as cerebral function improving agents | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0587193-A1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5280032-A | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| CN-1049662-A | Coumarin derivative, preparation thereof and application thereof in treating cerebrovascular disorder | SANKYO CO (JP) | 1991-03-06 | — | — | CN | disclosed |
| EP-0411912-A2 | Coumarin derivatives, their preparation and their use in the treatment of cerebrovascular disorders | Sankyo Company Limited (JP) | 1991-02-06 | — | — | EP | disclosed |
| EP-0383281-A1 | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-08-22 | — | — | EP | disclosed |
| US-4782054-A | ANTIISCHEMIC, ANTIHYPOXIC, STIMULANTS | ADIR ET COMPAGNIE (FR) | 1988-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259350-A1 | NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF | MET, RET, BRAF | DRD4 624/4885DRD2 873/4885DRD3 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.