Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695900 | 0.78 | SLC6A2 (0.47) | SLC6A2SLC6A4ELANEHTR7POLB | |
| SCHEMBL5215131 | 0.74 | SLC6A2 (0.77) | SLC6A2SLC6A4ELANE | |
| SCHEMBL5968777 | 0.71 | SLC6A2 (0.61) | SLC6A2SLC6A4ELANE | |
| SCHEMBL10816042 | 0.56 | SMN1; SMN2 (0.49) | SLC6A2ELANEPOLB | |
| SCHEMBL5213642 | 0.56 | SLC6A2 (0.66) | SLC6A2SLC6A4ELANE | |
| SCHEMBL1949985 | 0.54 | LMNA (0.64) | ELANEMGLLPOLB | |
| SCHEMBL13226476 | 0.54 | ELANE (0.64) | ELANEMGLLPOLB | |
| SCHEMBL13967214 | 0.53 | ELANE (0.53) | ELANEMGLLPOLB | |
| SCHEMBL16395894 | 0.52 | POLB (0.64) | ELANEMGLLPOLB | |
| SCHEMBL11862229 | 0.52 | ALOX5 (0.46) | SLC6A2ELANEHTR7MGLLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660065-A2 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005020976-A2 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |