SCHEMBL569596

SCHEMBL569596

c1nc(-c2nnc[nH]2)n[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15748053 0.76
SCHEMBL4319158 0.75
SCHEMBL12131262 0.72
SCHEMBL4108850 0.70 NISCH (0.42)
SCHEMBL1532939 0.68
SCHEMBL3021756 0.64 TYK2 (0.33)
SCHEMBL6306433 0.63 NOTUM (0.39)
SCHEMBL2658581 0.61 HSP90AA1 (0.32)
SCHEMBL21547877 0.60 L3MBTL1 (0.42)
SCHEMBL21547856 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470860-B2 Phenyl-sulfamates as aromatase inhibitors STERIX LIMITED (GB) 2013-06-25 US claimed
US-20020002193-A1 Thiadiazole antifungal agents YU DINGWEI TIM (US) 2002-01-03 US claimed
US-20010000512-A1 Novel class of piperazino substituted thiazoles YU DINGWEI TIM (US) 2001-04-26 US claimed
US-20010000177-A1 Novel class of thiomorpholino substituted thiazoles YU DINGWEI TIM (US) 2001-04-05 US claimed
US-20010000178-A1 PYRIDYL SUBSTITUTED THIAZOLES YU DINGWEI TIM (US) 2001-04-05 US claimed
US-20240225979-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR HAIR TREATMENT ODDITY LABS, LLC 2024-07-11 US disclosed
CN-106008473-A Compound resistant to bacterial angular leaf spot of tobacco and composition prepared from same 许庭庭 2016-10-12 CN disclosed
EP-1781664-B1 INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING METHYLGENE INC (CA) 2013-09-04 EP disclosed
EP-0116262-B1 FLUORAZOLYLPROPANOL DERIVATIVES AS MICROBICIDES AND PLANT GROWTH REGULATORS CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0116262-A2 Fluorazolylpropanol derivatives as microbicides and plant growth regulators CIBA-GEIGY AG (CH) 1984-08-22 EP disclosed
EP-0113644-A2 Halogen azolyl propane derivatives as microbicides and plant growth regulators CIBA-GEIGY AG (CH) 1984-07-18 EP disclosed
EP-0091398-A1 Microbicidal and plant growth regulating azolyl propane derivatives CIBA-GEIGY AG (CH) 1983-10-12 EP disclosed
EP-0082340-A1 Microbicidal triazolyl-ethyl-ethers CIBA-GEIGY AG (CH) 1983-06-29 EP disclosed
EP-0070798-A2 Microbicides and growth-regulating agents CIBA-GEIGY AG (CH) 1983-01-26 EP disclosed