Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882346 | 0.69 | MAPT (0.53) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL1903235 | 0.68 | PDE10A (0.45) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL16200225 | 0.67 | PDE10A (0.47) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL978864 | 0.63 | ALDH1A1 (0.42) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL2337144 | 0.63 | ALDH1A1 (0.46) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL569380 | 0.63 | PDPK1 (0.47) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL2637845 | 0.63 | PDE10A (0.43) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL1799678 | 0.63 | ALDH1A1 (0.63) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL569677 | 0.62 | POLB (0.49) | PDE10AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL1903302 | 0.62 | DCUN1D1 (0.44) | KDM4EHPGDALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |