Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 4/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12764207 | 0.75 | RAB9A (0.65) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL14477218 | 0.70 | TSHR (0.60) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL3359628 | 0.68 | TSHR (0.73) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL948085 | 0.66 | TSHR (0.64) | TSHRL3MBTL1SMN1; SMN2HSD17B10POLB | |
| SCHEMBL29482065 | 0.65 | TSHR (0.70) | TSHRL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL6003038 | 0.65 | RAB9A (0.46) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL1991359 | 0.65 | TSHR (0.78) | TSHRL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL1428305 | 0.65 | TSHR (0.56) | TSHRSMN1; SMN2 | |
| SCHEMBL221980 | 0.65 | RAB9A (0.53) | SLC9A1GRM2RAB9ANPC1MAPT | |
| SCHEMBL6008529 | 0.65 | RAB9A (0.53) | SLC9A1GRM2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670765-A2 | CETP INHIBITORS AND METABOLITES THEREOF | Pfizer Products Inc. (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005033082-A2 | CETP INHIBITORS AND METABOLITES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-04-14 | — | — | WO | disclosed |