Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221980 | 0.72 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL6008529 | 0.72 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL7227104 | 0.72 | SLC9A1 (0.55) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL1568148 | 0.72 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL7100624 | 0.72 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL30586926 | 0.72 | RAB9A (0.53) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL23057524 | 0.70 | RAB9A (0.64) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL13604201 | 0.70 | RAB9A (0.64) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL14489533 | 0.69 | RAB9A (0.58) | RAB9ANPC1L3MBTL1SLC9A1MAPT | |
| SCHEMBL24254311 | 0.69 | RAB9A (0.58) | RAB9ANPC1L3MBTL1SLC9A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |