SCHEMBL5696548

SCHEMBL5696548

COc1cc2nc3cc(N)c(OC)cc3nc2cc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.56
POLB P06746 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
GAA P10253 2/20 0.50
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 3/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
NPC1 O15118 1/20 0.44
USP2 O75604 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
PGK1 P00558 2/20 0.44
PKM P14618 1/20 0.44
THRB P10828 1/20 0.43
TLR8 Q9NR97 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922921 1.00 NQO2 (0.56) NQO2POLBL3MBTL1GAAALDH1A1
SCHEMBL11203601 0.89 POLB (0.47) NQO2POLBL3MBTL1GAAALDH1A1
SCHEMBL6110713 0.87 L3MBTL1 (0.45) NQO2POLBL3MBTL1GAAALDH1A1
SCHEMBL5696458 0.87 NQO2 (0.53) NQO2POLBL3MBTL1GAAALDH1A1
SCHEMBL31355401 0.87 NQO2 (0.53) NQO2POLBL3MBTL1GAAALDH1A1
SCHEMBL926329 0.79 L3MBTL1 (0.67) POLBL3MBTL1GAAALDH1A1CYP3A4
SCHEMBL31599834 0.79 S100B (0.50) POLBL3MBTL1GAAALDH1A1CYP3A4
SCHEMBL11199626 0.77 POLB (0.48) POLBL3MBTL1GAAALDH1A1CYP3A4
SCHEMBL453951 0.76 GAA (0.68) POLBL3MBTL1GAAALDH1A1CYP3A4
SCHEMBL4928310 0.76 NQO2 (0.50) NQO2POLBGAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891182-B1 ENZYME ASSISTED DYEING OF KERATINOUS FIBRES NOVOZYMES AS (DK) 2001-11-14 EP claimed
EP-0863950-B1 HAIR DYEING COMPOSITION NOVOZYMES AS (DK) 2001-10-10 EP claimed
EP-0865465-B1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVOZYMES AS (DK) 2001-05-30 EP claimed
EP-0865465-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1998-09-23 EP claimed
WO-1997019999-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1997-06-05 WO claimed
CN-111474796-B Electrochromic element and mobile terminal comprising same 宁波祢若电子科技有限公司 2022-10-14 CN disclosed
CN-111474796-A Electrochromic element and mobile terminal comprising same 宁波祢若电子科技有限公司 2020-07-31 CN disclosed
EP-0973875-B1 STORAGE-STABLE LIQUID FORMULATION COMPRISING A LACCASE NOVOZYMES AS (DK) 2006-06-14 EP disclosed
EP-1137391-B1 METHOD FOR TREATING HAIR NOVOZYMES AS (DK) 2004-11-03 EP disclosed
US-6667167-B1 Containing a polyalcohol such as a polyoxyalkylene glycol or ether, and a mono-, di-, oligo- or polysaccharides; pH that is more alkaline than the pH optimum of the laccase. NOVOZYMES A/S (DK) 2003-12-23 US disclosed
US-6572843-B1 Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide NOVOZYMES, A/S (DK) 2003-06-03 US disclosed
EP-1076494-B1 RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS NOVOZYMES AS (DK) 2002-09-18 EP disclosed
EP-0973875-A1 STORAGE-STABLE LIQUID FORMULATION COMPRISING A LACCASE NOVO NORDISK A/S (DK) 2000-01-26 EP disclosed
US-6001134-A PERMANENT HAIR DYE NOVO NORDISK A/S (DK) 1999-12-14 US disclosed
US-5948121-A PERMANENT DYEING OF KERATINOUS FIBERS. LACCASE DERIVED FROM A STRAIN OF THE GENUS MYCELIOPHTHORA NOVO NORDISK A/S (DK) 1999-09-07 US disclosed
US-5899212-A CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE NOVO NORDISK A/S (DK) 1999-05-04 US disclosed
WO-1999015137-A1 ENZYMATIC FOAM COMPOSITIONS FOR DYEING KERATINOUS FIBRES NOVO NORDISK A/S (DK) 1999-04-01 WO disclosed
EP-0865465-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1998-09-23 EP disclosed
WO-1998040471-A1 STORAGE-STABLE LIQUID FORMULATION COMPRISING A LACCASE NOVO NORDISK A/S (DK) 1998-09-17 WO disclosed
WO-1997019999-A1 LACCASES WITH IMPROVED DYEING PROPERTIES NOVO NORDISK A/S (DK) 1997-06-05 WO disclosed