SCHEMBL5696705

SCHEMBL5696705

COc1ccc(OC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2C9 P11712 1/20 0.66
CYP2C19 P33261 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
KMT2A Q03164 4/20 0.61
PRSS1 P07477 2/20 0.61
ACR P10323 2/20 0.61
MAPT P10636 1/20 0.61
GFER P55789 1/20 0.61
TDP1 Q9NUW8 1/20 0.59
ACHE P22303 1/20 0.58
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
GAA P10253 1/20 0.57
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
MAOA P21397 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9681395 1.00 LMNA (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9905861 1.00 LMNA (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9683087 1.00 LMNA (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL2610149 1.00 LMNA (0.66) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL24805747 0.95 SMN1; SMN2 (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL13038156 0.95 SMN1; SMN2 (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL16604889 0.95 SMN1; SMN2 (0.60) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL7591660 0.92 LMNA (0.75) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9663961 0.92 PRSS1 (0.69) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9666088 0.92 LMNA (0.75) LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339238-A1 IMAGE RECORDING METHOD AND INK JET-RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
EP-3790864-A1 QUINOLINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF Dongguan Hec Pesticides R&D Co., Ltd. (CN) 2021-03-17 EP disclosed
US-10330266-B2 LED with thermo-responsive black-body line dimming SIGNIFY HOLDING B.V. (NL) 2019-06-25 US disclosed
EP-2706402-B1 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2017-02-01 EP disclosed
US-9238775-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2016-01-19 US disclosed
US-9238775-B2 Switch element comprising a liquid-crystalline medium MERCK PATENT GMBH (DE) 2016-01-19 US disclosed
US-9222022-B2 Polymer-stabilized optical isotropic liquid crystal formulation and optical isotropic liquid crystal device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-12-29 US disclosed
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20130208227-A1 SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20080297703-A1 Optical Cellulose Acylate Film, Polarizing Plate And Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-12-04 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20070190268-A1 Optical film and optical compensatory film, polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-08-16 US disclosed
US-20070114492-A1 Silicon derivative, liquid crystal composition comprising the same and compensation film using the same liquid crystal composition LG CHEM, LTD. (KR) 2007-05-24 US disclosed
US-20070081115-A1 Polarizing plate and image display device using the same FUJIFILM CORPORATION (JP) 2007-04-12 US disclosed
EP-1118644-B1 Hot melt printing ink SIEGWERK DRUCKFARBEN AG (DE) 2006-06-14 EP disclosed
EP-1118644-A2 Hot melt printing ink Siegwerk Druckfarben GmbH & Co. KG (DE) 2001-07-25 EP disclosed
EP-0056519-B1 SHORT LENGTH ESTER LIQUID CRYSTAL MIXTURES Hughes Aircraft Company (US) 1986-08-06 EP disclosed
US-4427569-A Short length ester liquid crystal mixtures and process for making same HUGHES AIRCRAFT COMPANY (US) 1984-01-24 US disclosed