Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.61 |
| ▸ | ACR | P10323 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681395 | 1.00 | LMNA (0.66) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5696705 | 1.00 | LMNA (0.66) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9905861 | 1.00 | LMNA (0.66) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2610149 | 1.00 | LMNA (0.66) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL24805747 | 0.95 | SMN1; SMN2 (0.60) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL13038156 | 0.95 | SMN1; SMN2 (0.60) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16604889 | 0.95 | SMN1; SMN2 (0.60) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL7591660 | 0.92 | LMNA (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9663961 | 0.92 | PRSS1 (0.69) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9666088 | 0.92 | LMNA (0.75) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0354347-A2 | Liquid crystal compounds,their manufacture as modifiers for polycarbonates,polyestercarbonates and polyesters | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |