Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14011311 | 0.82 | HCAR2 (0.42) | ELANEPTGS2L3MBTL1LMNAATM | |
| 1'-Acetoxychavicol Acetate SCHEMBL17454871 | 0.81 | LMNA (0.47) | ELANEESR1HIF1ASMN1; SMN2LMNA | |
| 1'-Acetoxychavicol Acetate SCHEMBL3673490 | 0.81 | LMNA (0.47) | ELANEESR1HIF1ASMN1; SMN2LMNA | |
| SCHEMBL22130943 | 0.78 | LMNA (0.44) | ELANEESR1HIF1ASMN1; SMN2LMNA | |
| SCHEMBL21795326 | 0.77 | ELANE (0.79) | ELANEPTGS2L3MBTL1LMNAATM | |
| SCHEMBL18211356 | 0.76 | ELANE (0.66) | ELANEPTGS2ESR1HIF1ASMN1; SMN2 | |
| SCHEMBL7079093 | 0.75 | ELANE (0.59) | ELANEHIF1ASMN1; SMN2LMNATHRB | |
| SCHEMBL4904945 | 0.72 | ELANE (0.66) | ELANEPTGS2L3MBTL1LMNAATM | |
| SCHEMBL21325759 | 0.72 | ELANE (0.70) | ELANELMNACA2TDP1CYP2C9 | |
| SCHEMBL9641430 | 0.71 | ELANE (0.59) | ELANEPTGS2ROCK2ESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1700525-A2 | Pungent flavor components | Givaudan SA (CH) | 2006-09-13 | — | — | EP | disclosed |
| EP-0933030-B1 | Pungent flavor components | GIVAUDAN SA (CH) | 2006-07-26 | — | — | EP | disclosed |
| US-6504048-B1 | Flavorant compositions | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2003-01-07 | — | — | US | disclosed |
| US-6476252-B1 | Flavorant compositions | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2002-11-05 | — | — | US | disclosed |
| US-6203839-B1 | COMPRISING 1'-ACETOXYCHAVICOL ACETATE AND 1'-ACETOXYEUGENOL ACETATE DERIVATIVES AS WELL AS A FLAVORANT ACCEPTABLE CARRIER; MAY BE USED FOR FLAVORING FOODS, BEVERAGES OR HEALTHCARE PRODUCTS WITH WARM/HOT, SPICY AND PUNGENT SENSATIONS | GIVAUDN ROURE (INTERNATIONAL) SA (CH) | 2001-03-20 | — | — | US | disclosed |
| EP-0933030-A2 | Pungent flavor components | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1999-08-04 | — | — | EP | disclosed |