Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697129 | 0.85 | BRD4 (0.71) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL7167441 | 0.84 | BRD4 (1.00) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL21423949 | 0.75 | BRD4 (0.79) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL21410145 | 0.74 | BRD4 (0.77) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL21410459 | 0.74 | BRD4 (0.76) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL22916953 | 0.72 | BRD4 (0.73) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL7646032 | 0.71 | BRD4 (0.72) | BRD4HPGDLMNAALDH1A1HTT | |
| SCHEMBL11808831 | 0.71 | HPGD (0.73) | BRD4HPGDLMNAALDH1A1MEN1 | |
| SCHEMBL23174938 | 0.69 | BRD4 (0.67) | BRD4HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL21410242 | 0.69 | BRD4 (0.67) | BRD4HPGDLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100492-B1 | INDOLE sPLA2 INHIBITORS | LILLY CO ELI (US) | 2006-05-24 | — | — | EP | disclosed |
| US-6451839-B1 | Indole sPLA2 inhibitors | ELI LILLY AND COMPANY | 2002-09-17 | — | — | US | disclosed |