Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843394 | 0.87 | TYR (0.46) | CYSLTR2CYSLTR1TYRELANECTSG | |
| SCHEMBL28807252 | 0.86 | TYR (0.45) | CYSLTR2CYSLTR1TYRELANECTSG | |
| SCHEMBL23829701 | 0.85 | HPGD (0.42) | CYSLTR2CYSLTR1TYRHPGDKDM4E | |
| SCHEMBL27462004 | 0.83 | TYR (0.42) | CYSLTR2CYSLTR1TYRELANECTSG | |
| SCHEMBL27628607 | 0.82 | CTRC (0.41) | CYSLTR2CYSLTR1TYRELANECTSG | |
| SCHEMBL2927896 | 0.80 | TYR (0.42) | TYRHTTMEN1TP53CYP3A4 | |
| SCHEMBL1396205 | 0.80 | TLR8 (0.36) | TYRHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1005744 | 0.80 | TYR (0.56) | TYRELANECTSGHPGDKDM4E | |
| SCHEMBL28806211 | 0.80 | TLR4 (0.38) | CYSLTR2CYSLTR1HPGDKDM4EALDH1A1 | |
| SCHEMBL31539118 | 0.80 | HPGD (0.38) | CYSLTR2CYSLTR1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-B1 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-07-26 | — | — | EP | disclosed |
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |
| EP-0952997-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |
| WO-1998030609-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-07-16 | — | — | WO | disclosed |