SCHEMBL5697208

SCHEMBL5697208

C[Si](C)(C)c1ccc(C=O)c(O)c1[Si](C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 10/20 0.39
TYR P14679 2/20 0.38
TRIM24 O15164 2/20 0.38
TRIM33 Q9UPN9 2/20 0.38
TLR2 O60603 1/20 0.38
TLR1 Q15399 1/20 0.38
TLR6 Q9Y2C9 1/20 0.38
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
HSP90AA1 P07900 1/20 0.32
IDO1 P14902 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743110 0.78 MEN1 (0.31) MEN1KMT2AALDH1A1
SCHEMBL3966498 0.74 ERN1 (0.55) ERN1TRIM24TRIM33TLR2TLR1
SCHEMBL18604570 0.73 TDP1 (0.32) ALDH1A1
SCHEMBL31450219 0.71 ERN1 (0.59) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL17541404 0.71 ERN1 (0.59) ERN1TYRTRIM24TRIM33TLR2
SCHEMBL3971491 0.69 PADI4 (0.38) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL5711894 0.69 SELL (0.45) ERN1KDM4EMEN1KMT2AALDH1A1
SCHEMBL4301326 0.66 ALDH1A1 (0.32) ALDH1A1
SCHEMBL2007240 0.66 ERN1 (0.50) ERN1TRIM24TRIM33TLR2TLR1
SCHEMBL4074799 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1334107-B1 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2006-07-26 EP disclosed
EP-1334107-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS Basell Polyolefine GmbH (DE) 2003-08-13 EP disclosed
WO-2002032908-A2 NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2002-04-25 WO disclosed