Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198213 | 1.00 | TSHR (0.50) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL8755381 | 0.86 | MEN1 (0.40) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL13937393 | 0.84 | TSHR (0.61) | TSHRESR1ALDH1A1MEN1MAPT | |
| SCHEMBL3764158 | 0.80 | ESR1 (0.46) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL1200939 | 0.80 | AR (0.44) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL1201090 | 0.78 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ASLC6A2 | |
| SCHEMBL27837019 | 0.78 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ASLC6A2 | |
| SCHEMBL10836507 | 0.78 | ESR1 (0.45) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL13993318 | 0.78 | ESR1 (0.59) | TSHRESR1ALDH1A1GAAACP3 | |
| SCHEMBL7030620 | 0.77 | ESR1 (0.48) | TSHRESR1ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957083-B1 | Process for stabilising cyanhydrines | DSM FINE CHEM AUSTRIA GMBH (AT) | 2002-04-10 | — | — | EP | claimed |
| US-6031123-A | Process for stabilizing cyanohydrins | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2000-02-29 | — | — | US | claimed |
| EP-0957083-A2 | Process for stabilising cyanhydrines | DSM Fine Chemicals Austria GmbH (AT) | 1999-11-17 | — | — | EP | claimed |
| EP-0927766-B1 | Enzymatic process for the preparation of (S)-cyanhydrines | DSM FINE CHEM AUSTRIA GMBH (AT) | 2006-06-14 | — | — | EP | disclosed |
| WO-2004090124-A2 | SEQUENCES ENCODING S-HYDROXYNITRIL LYASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CYANOHYDRINS | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | WO | disclosed |
| EP-1223168-A1 | Method for the preparation of enantiomerically enriched amino and hydroxyfuranones | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2002-07-17 | — | — | EP | disclosed |
| US-6417377-B1 | Process for preparing enantiomer-enriched amino- and hydroxyfuranones | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-07-09 | — | — | US | disclosed |
| EP-0957083-B1 | Process for stabilising cyanhydrines | DSM FINE CHEM AUSTRIA GMBH (AT) | 2002-04-10 | — | — | EP | disclosed |
| US-6225095-B1 | REACTING ALDEHYDE OR KETONE DISSOLVED IN AN ORGANIC, WATER-IMMISCIBLE OR SLIGHTLY MISCIBLE DILUENT, AN AQUEOUS HYDROXYNITRILE LYASE SOLUTION, AND A CYANIDE GROUP DONOR TO FORM AN EMULSION WHICH IS MAINTAINED BY STIRRING | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2001-05-01 | — | — | US | disclosed |
| US-6031123-A | Process for stabilizing cyanohydrins | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2000-02-29 | — | — | US | disclosed |
| EP-0957083-A2 | Process for stabilising cyanhydrines | DSM Fine Chemicals Austria GmbH (AT) | 1999-11-17 | — | — | EP | disclosed |
| EP-0927766-A1 | Enzymatic process for the preparation of (S)-cyanhydrines | DSM Fine Chemicals Austria GmbH (AT) | 1999-07-07 | — | — | EP | disclosed |