Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697209 | 1.00 | TSHR (0.50) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL8755381 | 0.86 | MEN1 (0.40) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL13937393 | 0.84 | TSHR (0.61) | TSHRESR1ALDH1A1MEN1MAPT | |
| SCHEMBL3764158 | 0.80 | ESR1 (0.46) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL1200939 | 0.80 | AR (0.44) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL1201090 | 0.78 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ASLC6A2 | |
| SCHEMBL27837019 | 0.78 | TSHR (0.50) | TSHRALDH1A1LMNAKMT2ASLC6A2 | |
| SCHEMBL10836507 | 0.78 | ESR1 (0.45) | TSHRESR1ALDH1A1MEN1LMNA | |
| SCHEMBL13993318 | 0.78 | ESR1 (0.59) | TSHRESR1ALDH1A1GAAACP3 | |
| SCHEMBL7030620 | 0.77 | ESR1 (0.48) | TSHRESR1ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985572-B2 | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF SE (DE) | 2011-07-26 | — | — | US | claimed |
| EP-1599584-B1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF SE (DE) | 2009-07-01 | — | — | EP | claimed |
| CN-100445375-C | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2008-12-24 | — | — | CN | claimed |
| US-20060259999-A1 | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-16 | — | — | US | claimed |
| CN-1753990-A | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2006-03-29 | — | — | CN | claimed |
| EP-1599584-A1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-30 | — | — | EP | claimed |
| WO-2004076655-A1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-10 | — | — | WO | claimed |
| EP-0957083-B1 | Process for stabilising cyanhydrines | DSM FINE CHEM AUSTRIA GMBH (AT) | 2002-04-10 | — | — | EP | claimed |
| US-6031123-A | Process for stabilizing cyanohydrins | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2000-02-29 | — | — | US | claimed |
| EP-0527553-B1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1997-05-07 | — | — | EP | claimed |
| US-5296373-A | Stereoselective hydrolysis of mandelonitrile in neutral or basic aqueous medium | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-22 | — | — | US | claimed |
| EP-0527553-A1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-02-17 | — | — | EP | claimed |
| US-11649204-B2 | Process for the preparation of trifloxystrobin | HIKAL LIMITED (IN) | 2023-05-16 | — | — | US | disclosed |
| US-11649204-B2 | Process for the preparation of trifloxystrobin | HIKAL LIMITED (IN) | 2023-05-16 | — | — | US | disclosed |
| CN-108368033-B | Method for preparing trifloxystrobin | GSP作物科学有限公司 | 2021-05-04 | — | — | CN | disclosed |
| US-20200283373-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN | HIKAL LIMITED (IN) | 2020-09-10 | — | — | US | disclosed |
| US-5296373-A | Stereoselective hydrolysis of mandelonitrile in neutral or basic aqueous medium | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0561637-A2 | A catalyst for asymmetric induction | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0527553-A1 | Process for producing r(-)-mandelic acid and derivative thereof | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-02-17 | — | — | EP | disclosed |
| US-5145980-A | OXIME ETHERS, AND FUNGICIDES CONTAINING SAME | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649204-B2 | Process for the preparation of trifloxystrobin | CYP3A7, CYP51A1, TREH | TSHR 1670/4885ESR1 4081/4885ALDH1A1 539/4885 |
| US-20200283373-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF TRIFLOXYSTROBIN | SI, TREH, CYP3A7 | TSHR 1674/4885ESR1 4351/4885ALDH1A1 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.