Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332219 | 0.82 | TSHR (0.40) | TSHRALDH1A1LMNASGMS2TRPA1 | |
| SCHEMBL29031397 | 0.81 | ESR1 (0.48) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL954806 | 0.79 | ESR1 (0.46) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL29433705 | 0.79 | ESR1 (0.46) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL10519770 | 0.77 | ESR1 (0.45) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL11453434 | 0.77 | ESR1 (0.45) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL9501889 | 0.77 | TRPA1 (0.50) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL5697209 | 0.77 | TSHR (0.50) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL198213 | 0.77 | TSHR (0.50) | ESR1TSHRACP3ACHEALDH1A1 | |
| SCHEMBL13773379 | 0.76 | GABRA1 (0.44) | TSHRALDH1A1LMNAKMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | claimed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | claimed |
| US-4048212-A | Process for the manufacture of 1,4-dicyanonaphthalenes | CIBA-GEIGY CORPORATION (US) | 1977-09-13 | — | — | US | claimed |
| JP-7285924-A | — | — | None | — | — | JP | disclosed |
| US-12392042-B2 | Alternating current (AC) transition-metal catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2025-08-19 | — | — | US | disclosed |
| US-20230407492-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-12-21 | — | — | US | disclosed |
| EP-4214355-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | Yeda Research and Development Co. Ltd (IL) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022059010-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-03-24 | — | — | WO | disclosed |
| CN-112494653-A | Combination of IRS/STAT3 dual modulators and anticancer agents for the treatment of cancer | 特尔诺沃有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-112353938-A | Combination of IRS/STAT3 dual modulators and anticancer agents for the treatment of cancer | 特尔诺沃有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-107250108-B | Combination of IRS/STAT3 dual modulators and anticancer agents for the treatment of cancer | 特尔诺沃有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-110950778-A | Process and catalyst system for preparing aromatic malononitrile | 安徽省化工研究院 | 2020-04-03 | — | — | CN | disclosed |
| US-8946188-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-01-23 | — | — | US | disclosed |
| US-8461128-B2 | Anti-microbial agents and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2013-06-11 | — | — | US | disclosed |
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | disclosed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | disclosed |
| JP-H07285924-A | BENZOFLUORENE COMPOUND AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING THE SAME | RICOH CO LTD | 1995-10-31 | — | — | JP | disclosed |
| US-4048212-A | Process for the manufacture of 1,4-dicyanonaphthalenes | CIBA-GEIGY CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024611-A1 | ANTI-MICROBIAL AGENTS AND USES THEREOF | ACAT1, ACAT2, APEH | ESR1 4503/4885TSHR 1484/4885ACP3 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.