Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.51 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697471 | 1.00 | MBOAT4 (0.51) | MBOAT4NR1I3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL8898524 | 0.86 | MBOAT4 (0.52) | MBOAT4NR1I3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL1570884 | 0.80 | CYP19A1 (0.53) | CYP19A1SHBG | |
| SCHEMBL22558402 | 0.80 | CYP19A1 (0.53) | CYP19A1SHBG | |
| SCHEMBL4942914 | 0.79 | SHBG (0.46) | GRIN1GRIN2BCYP19A1SHBG | |
| SCHEMBL9789978 | 0.79 | MBOAT4 (0.55) | MBOAT4NR1I3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL9789976 | 0.79 | MBOAT4 (0.49) | MBOAT4NR1I3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL5055953 | 0.78 | NR1I3 (0.48) | MBOAT4NR1I3GRIN1GRIN2BCYP19A1 | |
| SCHEMBL7079588 | 0.75 | SHBG (0.40) | CYP19A1SHBG | |
| SCHEMBL7084759 | 0.75 | MBOAT4 (0.51) | MBOAT4NR1I3GRIN1GRIN2BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658083-A1 | ENHANCEMENT OF ACTIVITY AND/OR DURATION OF ACTION OF SELECTED ANTI-INFLAMMATORY STEROIDS | BODOR, Nicholas S. (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2004112800-A1 | ENHANCEMENT OF ACTIVITY AND/OR DURATION OF ACTION OF SELECTED ANTI-INFLAMMATORY STEROIDS | BODOR NICHOLAS S (US) | 2004-12-29 | — | — | WO | disclosed |