Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697501 | 0.88 | MAPK14 (0.40) | GCK | |
| SCHEMBL1680815 | 0.85 | PDPK1 (0.41) | ADORA2AADORA1 | |
| SCHEMBL1681150 | 0.83 | KDM5A (0.41) | LOXLOXL2KLKB1ADORA2AADORA1 | |
| SCHEMBL1681092 | 0.80 | KLKB1 (0.41) | LOXLOXL2PIN1KLKB1GCK | |
| SCHEMBL1680495 | 0.80 | KLKB1 (0.44) | LOXLOXL2PIN1KLKB1SLC8A1 | |
| SCHEMBL1680873 | 0.78 | POLB (0.42) | LOXLOXL2ADORA2AALDH1A1 | |
| SCHEMBL14534354 | 0.78 | PDPK1 (0.35) | GCKNPSR1ALDH1A1 | |
| SCHEMBL1680964 | 0.76 | SLC8A1 (0.45) | KLKB1GCKSLC8A1 | |
| SCHEMBL12352596 | 0.76 | SCN9A (0.41) | PIN1GCKADORA2AADORA1NPSR1 | |
| SCHEMBL1680976 | 0.76 | EGLN1 (0.47) | LOXLOXL2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |