SCHEMBL1680964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680799	0.89	GCK (0.42)	SLC8A1KMT2AMEN1KLKB1P2RY14
	SCHEMBL1680495	0.88	KLKB1 (0.44)	SLC8A1KLKB1P2RY14
	SCHEMBL1680902	0.88	SLC8A1 (0.49)	SLC8A1KMT2AP2RY14KDM4ELMNA
	SCHEMBL12737244	0.88	GABRA5 (0.43)	SLC8A1KMT2AKLKB1P2RY14GCK
	SCHEMBL1681072	0.85	HCAR3 (0.47)	KMT2AMEN1KLKB1GCKMAPT
	SCHEMBL1681245	0.84	KLKB1 (0.37)	SLC8A1KLKB1P2RY14
	SCHEMBL1681232	0.83	GCK (0.42)	SLC8A1KMT2AMEN1KLKB1P2RY14
	SCHEMBL1680841	0.82	GCK (0.42)	KLKB1P2RY14GCKKDM4EMAPT
	SCHEMBL1680976	0.82	EGLN1 (0.47)	KLKB1TP53
	SCHEMBL1681242	0.82	KLKB1 (0.36)	SLC8A1KLKB1P2RY14GCKTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.