SCHEMBL1680495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680964	0.88	SLC8A1 (0.45)	KLKB1SLC8A1P2RY14
	SCHEMBL1681169	0.88	EPHX2 (0.53)	EPHX2CDK8HDAC1HDAC6LOX
	SCHEMBL1681074	0.88	CDK8 (0.45)	KLKB1EPHX2CDK8SLC8A1HDAC1
	SCHEMBL1680696	0.88	MAPK14 (0.46)	EPHX2CDK8HDAC1HDAC6PTGER4
	SCHEMBL1680509	0.88	EPHX2 (0.49)	EPHX2HDAC1HDAC6
	SCHEMBL1680799	0.87	GCK (0.42)	KLKB1SLC8A1P2RY14DGAT2
	SCHEMBL1680979	0.86	VNN1 (0.45)	KLKB1EPHX2LOXLOXL2
	SCHEMBL1681072	0.83	HCAR3 (0.47)	KLKB1LOXLOXL2
	SCHEMBL1681092	0.82	KLKB1 (0.41)	KLKB1P2RY14LOXLOXL2PIN1
	SCHEMBL1681245	0.82	KLKB1 (0.37)	KLKB1SLC8A1P2RY14DGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.