Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991486 | 0.92 | MAPT (0.61) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL20832 | 0.90 | ALDH1A1 (0.60) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL3776491 | 0.88 | MAPT (0.46) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL9871326 | 0.88 | FTO (0.56) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL5477976 | 0.87 | HPGD (0.48) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL4230526 | 0.86 | ALDH1A1 (0.53) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL6652238 | 0.86 | HPGD (0.47) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL1029702 | 0.86 | ALDH1A1 (0.67) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| Naphthalene SCHEMBL351805 | 0.86 | HPGD (0.59) | HPGDALDH1A1ALOX12CYP2C9ALOX15 | |
| SCHEMBL9878722 | 0.86 | ALDH1A1 (0.56) | HPGDALDH1A1ALOX12CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667733-A1 | A METHOD OF EVALUATING ORGAN FUNCTION | Oxygenix Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030264-A1 | A METHOD OF EVALUATING ORGAN FUNCTION | OXYGENIX CO., LTD. (JP) | 2005-04-07 | — | — | WO | disclosed |