SCHEMBL5697805

SCHEMBL5697805

CCCC(=O)NCc1cccc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
KMT2A Q03164 1/20 0.57
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
GAA P10253 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
LMNA P02545 1/20 0.54
HPGD P15428 1/20 0.54
HTT P42858 1/20 0.54
MTNR1A P48039 1/20 0.53
ATM Q13315 1/20 0.52
CHRNB2 P17787 1/20 0.52
CHRNA4 P43681 1/20 0.52
P2RX7 Q99572 1/20 0.52
TERT O14746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6647843 0.92 HTT (0.65) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL1284855 0.89 KMT2A (0.59) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL17537295 0.87 KMT2A (0.57) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL6495378 0.84 MTNR1A (0.67) MTNR1A
SCHEMBL8303720 0.83 MTNR1A (0.56) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL1291448 0.83 MEN1 (0.57) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL31248353 0.83 KMT2A (0.56) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL28710258 0.83 SMN1; SMN2 (0.56) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL13073769 0.82 KMT2A (0.59) MEN1MAPTKMT2AGAASMN1; SMN2
SCHEMBL27548891 0.82 KMT2A (0.59) MEN1MAPTKMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833633-A4 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 1999-03-24 EP claimed
EP-0833633-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 1998-04-08 EP claimed
WO-2016028571-A2 DIPEPTIDOMIMETICS AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES CORNELL UNIVERSITY (US) 2016-02-25 WO disclosed
US-7186786-B2 Chain transfer agents for RAFT polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2007-03-06 US disclosed
US-7179872-B2 Chain transfer agents for RAFT polymerization in aqueous media UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2007-02-20 US disclosed
EP-1675824-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS Oy Juvantia Pharma Ltd (FI) 2006-07-05 EP disclosed
WO-2005033069-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS OY JUVANTIA PHARMA LTD (FI) 2005-04-14 WO disclosed
EP-0833633-A4 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 1999-03-24 EP disclosed
EP-0833633-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 1998-04-08 EP disclosed
WO-1996039137-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-12-12 WO disclosed