Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036088 | 0.93 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL8065745 | 0.89 | MTNR1A (0.68) | MTNR1APTPN1 | |
| SCHEMBL919204 | 0.87 | MTNR1A (0.64) | MTNR1AMTNR1BPTPN1 | |
| SCHEMBL919206 | 0.87 | MTNR1A (0.64) | MTNR1AMTNR1BPTPN1 | |
| SCHEMBL9131472 | 0.85 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL30444049 | 0.85 | MTNR1A (0.59) | MTNR1AMTNR1B | |
| SCHEMBL5349352 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL4036596 | 0.84 | MTNR1A (0.69) | MTNR1AMTNR1BPTPN1 | |
| SCHEMBL11255122 | 0.84 | MTNR1A (0.56) | MTNR1A | |
| SCHEMBL5697805 | 0.84 | MEN1 (0.57) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946468-B1 | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors | ZENECA LIMITED (GB) | 2005-09-20 | — | — | US | disclosed |
| CN-1155562-C | Novel naphthalene compounds, process for their preparation and pharmaceutical compositions containing them | ɪά��ʵ���� | 2004-06-30 | — | — | CN | disclosed |
| US-6143789-A | ENANTIOMORPHS | ADIR ET COMPAGNIE (FR) | 2000-11-07 | — | — | US | disclosed |
| CN-1221734-A | Novel naphthalene compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-07-07 | — | — | CN | disclosed |
| EP-0919541-A1 | Naphthalene compounds, process for their preparation and their pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 1999-06-02 | — | — | EP | disclosed |
| US-5420158-A | Melatonin activity | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |