Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697901 | 0.86 | KCNA5 (0.56) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL3162863 | 0.83 | KCNA5 (0.75) | KCNA5KCNA3KCNK3TAS1R3TAS1R1 | |
| SCHEMBL2208589 | 0.83 | KCNA5 (0.68) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL5697899 | 0.82 | TAS1R3 (0.49) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL5697905 | 0.82 | KCNA5 (0.49) | RAB9AKCNA5KCNA3KCNK3TAS1R3 | |
| SCHEMBL727201 | 0.81 | KCNA5 (0.76) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL5697890 | 0.81 | KCNA5 (0.76) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL5697922 | 0.80 | KCNA5 (0.54) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL5697829 | 0.80 | ALDH1A1 (0.49) | RAB9ANPC1KCNA5KCNA3KCNK3 | |
| SCHEMBL5697836 | 0.80 | KCNA5 (0.69) | RAB9ANPC1KCNA5SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222163-B1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-07-12 | — | — | EP | disclosed |