Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 3/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421432 | 0.87 | PLA2G10 (0.43) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4007883 | 0.83 | PLA2G10 (0.42) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4007726 | 0.83 | PLA2G10 (0.42) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4010272 | 0.82 | PLA2G10 (0.41) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4203049 | 0.81 | ALDH1A1 (0.40) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4010269 | 0.78 | PLA2G10 (0.39) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4013614 | 0.77 | CACNA2D1 (0.39) | PLA2G10LMNAPOLBCACNA2D1CACNB3 | |
| SCHEMBL4008964 | 0.77 | DPP4 (0.38) | PLA2G10CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL4010151 | 0.77 | DPP4 (0.38) | PLA2G10CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL4008282 | 0.77 | DPP4 (0.38) | PLA2G10CACNA2D1CACNB3CACNA1CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670750-A1 | PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE ALPHA2DELTA- PROTEIN | Warner-Lambert Company LLC (US) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030703-A1 | PRODRUGS OF AMINO ACIDS WITH AFFINITY FOR THE α2δ- PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2005-04-07 | — | — | WO | claimed |