Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 4/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698146 | 0.87 | PLA2G10 (0.42) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4015335 | 0.84 | PLA2G10 (0.43) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4005328 | 0.84 | PLA2G10 (0.43) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4008884 | 0.84 | PLA2G10 (0.43) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4009802 | 0.83 | PLA2G10 (0.42) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4211648 | 0.82 | PLA2G10 (0.40) | PLA2G10PLA2G2CCACNA2D1CACNB3CACNA1C | |
| SCHEMBL4014313 | 0.81 | PLA2G10 (0.40) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4009547 | 0.80 | PLA2G10 (0.41) | PLA2G10PLA2G2CPOLBCACNA2D1CACNB3 | |
| SCHEMBL4014168 | 0.78 | DPP8 (0.42) | PLA2G10CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL4010164 | 0.78 | DPP8 (0.42) | PLA2G10CACNA2D1CACNB3CACNA1CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070483-A1 | Prodrugs of amino acids with affinity for the alpha2delta-protein | VIATRIS SPECIALTY LLC. | 2005-03-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070483-A1 | Prodrugs of amino acids with affinity for the alpha2delta-protein | SCN2A, OPRD1, SCN1A | PLA2G10 2762/4885PLA2G2C 1607/4885POLB 3619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.