Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652059 | 0.68 | MAOB (0.37) | HCAR2KDM1AMAOBHDAC9 | |
| SCHEMBL5796055 | 0.66 | HDAC9 (0.50) | HCAR2KDM1AMAOBHDAC9 | |
| SCHEMBL3053835 | 0.66 | KDM1A (0.43) | HCAR2KDM1AMAOBHDAC9 | |
| SCHEMBL19130584 | 0.66 | HDAC9 (0.50) | HCAR2KDM1AMAOBHDAC9 | |
| SCHEMBL19130585 | 0.63 | KDM1A (0.41) | KDM1AMAOBHDAC9 | |
| SCHEMBL6289733 | 0.63 | KDM1A (0.41) | KDM1AMAOBHDAC9 | |
| SCHEMBL6285519 | 0.63 | HDAC4 (0.44) | KDM1AMAOBHDAC9 | |
| SCHEMBL7885283 | 0.62 | BRD4 (0.40) | KDM1AMAOBHDAC9 | |
| SCHEMBL5871752 | 0.61 | CYP3A4 (0.57) | KDM1AMAOBHDAC9 | |
| SCHEMBL1535911 | 0.61 | KDM1A (0.48) | HCAR2KDM1AMAOBHDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250342-B1 | BRIDGED METALLOCENE COMPOUNDS AS OLEFIN-POLYMERIZATION CATALYSTS | POLIMERI EUROPA SPA (IT) | 2006-06-28 | — | — | EP | disclosed |
| US-6984703-B1 | Bridged metallocene compounds as olefin-polymerization catalysts | POLIMERI EUROPA S.P.A. (IT) | 2006-01-10 | — | — | US | disclosed |