SCHEMBL6289733

SCHEMBL6289733

Cc1ccccc1C1(O)CCc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.41
MAOB P27338 1/20 0.41
HDAC4 P56524 1/20 0.40
KIF11 P52732 1/20 0.40
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
OPRL1 P41146 1/20 0.40
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.38
BRD4 O60885 1/20 0.38
HDAC9 Q9UKV0 1/20 0.37
SIGMAR1 Q99720 2/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19130585 1.00 KDM1A (0.41) KDM1AMAOBHDAC4KIF11OPRM1
SCHEMBL7171860 0.81 PDK2 (0.43) SIGMAR1TSHR
SCHEMBL3053835 0.81 KDM1A (0.43) KDM1AMAOBMAPK1SMN1; SMN2LMNA
SCHEMBL6946652 0.77 SIGMAR1 (0.55) KDM1AMAOBOPRM1OPRD1OPRK1
SCHEMBL19130584 0.77 HDAC9 (0.50) KDM1AMAOBBRD4HDAC9SIGMAR1
SCHEMBL5796055 0.77 HDAC9 (0.50) KDM1AMAOBBRD4HDAC9SIGMAR1
SCHEMBL6285519 0.74 HDAC4 (0.44) KDM1AMAOBHDAC4MAPK1SMN1; SMN2
SCHEMBL7885283 0.73 BRD4 (0.40) KDM1AMAOBSMN1; SMN2LMNABRD4
SCHEMBL3941515 0.72 KDM1A (0.46) KDM1AMAOBMAPK1SMN1; SMN2LMNA
SCHEMBL19130582 0.72 KDM1A (0.46) KDM1AMAOBMAPK1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US disclosed
US-20030195308-A1 Catalyst systems for high melting thermoplastic elastomeric alpha-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-10-16 US disclosed
US-6566544-B1 Indene ring-containing metallocene-complex catalysts THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY 2003-05-20 US disclosed
US-6559262-B1 An elastomeric amorphous-crystalline blocks copolymer of at least one alpha olefin monomor with ethylene having less than 10 mole % ethylene units, said ethylene is incorporated randomly between the olefin units in the polymer chain with a THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY 2003-05-06 US disclosed
US-6160064-A POLYMERIZING MONOMERS IN PRESENCE OF CATALYST SYSTEM COMPRISING UNBRIDGED FLUXIONAL METALLOCENE AND COCATALYST, INTRODUCING ETHYLENE INTO SYSTEM TO INDUCE POLYMERIZATION RATE ENHANCEMENT/ELASTOMERIC PROPERTY ENHANCING EFFECTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-12-12 US disclosed
US-5969070-A HOMOGENEOUS COMPOSITION FORMED FROM LINEAR OR BRANCHED CHAIN C3 TO C10 MONOMERS SUCH AS PROPYLENE, 1-BUTENE, 1-PENTENE, 4-METHYL-1-PENTENE, 1-HEXENE AND MIXTURES THEREOF, COMPRISING ALTERNATING ISOTACTIC AND ATACTIC DISASTEREOSEQUENCES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1999-10-19 US disclosed
EP-0802935-A4 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS UNIV LELAND STANFORD JUNIOR (US) 1998-09-30 EP disclosed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP disclosed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO disclosed