Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130584 | 1.00 | HDAC9 (0.50) | HDAC9BRD4KDM1AMAOBCYP3A4 | |
| SCHEMBL6316631 | 0.90 | PGR (0.47) | HDAC9BRD4KDM1ACYP3A4CYP17A1 | |
| SCHEMBL9906167 | 0.89 | KDM1A (0.49) | HDAC9BRD4KDM1APGRTSHR | |
| SCHEMBL7885283 | 0.87 | BRD4 (0.40) | HDAC9BRD4KDM1AMAOBCYP3A4 | |
| SCHEMBL5871752 | 0.85 | CYP3A4 (0.57) | HDAC9BRD4KDM1AMAOBCYP3A4 | |
| SCHEMBL28076879 | 0.81 | CYP3A4 (0.56) | CYP3A4SIGMAR1 | |
| SCHEMBL3053835 | 0.80 | KDM1A (0.43) | HDAC9KDM1AMAOBHCAR2TSHR | |
| SCHEMBL8865954 | 0.79 | BRD4 (0.38) | HDAC9BRD4KDM1AMAOBCYP3A4 | |
| SCHEMBL8865370 | 0.78 | OPRM1 (0.49) | KDM1ACYP3A4ALDH1A1SIGMAR1 | |
| SCHEMBL19130585 | 0.77 | KDM1A (0.41) | HDAC9BRD4KDM1AMAOBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104869845-B | Blistering auxiliary agent and its production method | 雀巢产品技术援助有限公司 | 2018-04-20 | — | — | CN | claimed |
| US-5576139-A | EXCELLENT RESOLUTION, SENSITIVITY, HEAT RESISTANCE AND DEVELOPABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-19 | — | — | US | claimed |
| EP-0160508-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-31 | — | — | EP | claimed |
| US-10196338-B2 | Chiral diamine compounds for the preparation of chiral alcohols and chiral amines | UNIVERSITY COLLEGE DUBLIN (IE) | 2019-02-05 | — | — | US | disclosed |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | UNIVERSITY COLLEGE DUBLIN (IE) | 2017-07-20 | — | — | US | disclosed |
| EP-3148978-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOL AND CHIRAL AMINE | UNIVERSITY COLLEGE DUBLIN (IE) | 2017-04-05 | — | — | EP | disclosed |
| CN-105130758-A | Method for preparing bisphenol A by adopting combined process of suspension crystallization and falling film crystallization | NANTONG XINGCHEN SYNTHETIC MATERIAL CO LTD | 2015-12-09 | — | — | CN | disclosed |
| WO-2015181182-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOL AND CHIRAL AMINE | UNIVERSITY COLLEGE DUBLIN (IE) | 2015-12-03 | — | — | WO | disclosed |
| US-20140088303-A1 | PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | SEKISUI MEDICAL CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| US-20140088303-A1 | PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | SEKISUI MEDICAL CO., LTD. (JP) | 2014-03-27 | — | — | US | disclosed |
| US-8624024-B2 | Phosphoramide compound, method for producing the same, ligand, complex, catalyst and method for producing optically active alcohol | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-01-07 | — | — | US | disclosed |
| WO-2000044810-A1 | METHOD FOR PREPARING COPOLYCARBONATES OF ENHANCED CRYSTALLINITY | GENERAL ELECTRIC COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| US-6060576-A | Method for preparing copolycarbonates of enhanced crystallinity | GENERAL ELECTRIC COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0946574-A1 | 3-ARYL SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5959047-A | AN AROMATIC COMPLEX OF TITANIUM OR ZIRCONIUM OR HAFNIUM USED FOR POLYMERIZATION OF OLEFIN; | THE DOW CHEMICAL COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| US-5866704-A | 3-aryl substituted indenyl containing metal complexes and polymerization process | THE DOW CHEMICAL COMPANY (US) | 1999-02-02 | — | — | US | disclosed |
| US-5780659-A | ADDITION POLYMERIZATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998027102-A1 | 3-ARYL SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |
| EP-0798306-A1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5576139-A | EXCELLENT RESOLUTION, SENSITIVITY, HEAT RESISTANCE AND DEVELOPABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196338-B2 | Chiral diamine compounds for the preparation of chiral alcohols and chiral amines | ADH1C, ADH1A, ADH5 | HDAC9 4177/4885BRD4 3427/4885KDM1A 2595/4885 |
| US-20170204036-A1 | CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOLS AND CHIRAL AMINES | ADH1C, ADH1A, ADH5 | HDAC9 4122/4885BRD4 3517/4885KDM1A 2341/4885 |
| US-20140088303-A1 | PHOSPHORAMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, LIGAND, COMPLEX, CATALYST AND METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1C, ADH1A, DERA | HDAC9 1090/4885BRD4 2408/4885KDM1A 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.