4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL569852

CC(O)CC(C)O.Cc1ccc(C(=O)O)cc1.Cc1ccc(C(=O)O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
SRD5A2 P31213 3/20 0.61
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
LMNA P02545 1/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA9 Q16790 2/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
CSNK2A2 P19784 1/20 0.44
CSNK2B P67870 1/20 0.44
CSNK2A1 P68400 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL4578677 1.00 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
4-Methylbenzoic Acid SCHEMBL19570770 0.88 SRD5A2 (0.57) ALDH1A1SMN1; SMN2SRD5A2TSHRLMNA
4-Methylbenzoic Acid SCHEMBL5081494 0.88 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
4-Methylbenzoic Acid SCHEMBL1786349 0.88 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Benzoic Acid SCHEMBL560829 0.83 TSHR (0.61) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Benzoic Acid SCHEMBL4577010 0.83 TSHR (0.61) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Benzoic Acid SCHEMBL1068956 0.83 TSHR (0.61) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Benzoic Acid SCHEMBL1073214 0.83 TSHR (0.61) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
Terephthalic Acid SCHEMBL526449 0.82 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR
4-Methylbenzoic Acid SCHEMBL11366477 0.82 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024088298-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2024-05-02 WO claimed
US-9068026-B2 Magnesium halide adducts, catalyst components and catalysts comprising the same, and preparation processes thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2015-06-30 US claimed
US-20120302708-A1 MAGNESIUM HALIDE ADDUCTS, CATALYST COMPONENTS AND CATALYSTS COMPRISING THE SAME, AND PREPARATION PROCESSES THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-11-29 US claimed
WO-2025042454-A1 CATALYST SYSTEM FOR ENHANCED STEREO-SPECIFICITY OF OLEFIN POLYMERIZATION FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-02-27 WO disclosed
US-20250066513-A1 Catalyst System For Enhanced Stereo-Specificity Of Olefin Polymerization FORMOSA PLASTICS CORP USA (US) 2025-02-27 US disclosed
US-20250026868-A1 OLEFIN POLYMERIZATION ZIEGLER-NATTA CATALYST COMPONENTS ANDPROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS THEREWITH FORMOSA PLASTICS CORPORATION, USA (US) 2025-01-23 US disclosed
WO-2024088298-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2024-05-02 WO disclosed
US-20230091516-A1 Olefin polymerization Ziegler-Natta catalyst components and process for the production of olefin polymers therewith FORMOSA PLASTICS CORP USA (US) 2023-03-23 US disclosed
US-20230092187-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT HAVING CARBONATE COMPOUNDS FORMOSAPLASTICSCORPORATION USA (US) 2023-03-23 US disclosed
EP-3397658-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2022-07-27 EP disclosed
US-11117982-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2021-09-14 US disclosed
EP-2225288-A1 SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR Dow Global Technologies Inc. (US) 2010-09-08 EP disclosed
EP-2185600-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE Dow Global Technologies Inc. (US) 2010-05-19 EP disclosed
WO-2009085649-A1 SELF-LIMITING CATALYST COMPOSITION WITH BIDENTATE INTERNAL DONOR DOW GLOBAL TECHNOLOGIES INC. (US) 2009-07-09 WO disclosed
WO-2009029447-A1 SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE DOW GLOBAL TECHNOLOGIES INC. (US) 2009-03-05 WO disclosed
EP-1666505-A1 CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF China Petroleum & Chemical Corporation (CN) 2006-06-07 EP disclosed
EP-1478617-A4 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL (CN) 2006-04-19 EP disclosed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 ALDH1A1 3489/4885SMN1; SMN2 3701/4885SRD5A2 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.