Terephthalic Acid

Terephthalic Acid

SCHEMBL526449

Cc1ccc(C)cc1.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
SRD5A2 P31213 3/20 0.85
TSHR P16473 3/20 0.71
TP53 P04637 1/20 0.71
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
LMNA P02545 2/20 0.65
RXRA P19793 1/20 0.60
RXRB P28702 1/20 0.60
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL93638 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL147465 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL11366477 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL15994097 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1331178 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6113245 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6914468 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6112949 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1042425 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6912547 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025092815-A1 SKIN MATERIAL FOR VEHICLE AND VEHICLE DECORATION COMPRISING SKIN MATERIAL 延锋国际汽车技术有限公司 2025-05-08 WO claimed
WO-2024255824-A1 RECYCLABLE SKIN FOR INTERIOR OF VEHICLE AND VEHICLE INTERIOR COMPONENT COMPRISING SAME 延锋国际汽车技术有限公司 2024-12-19 WO claimed
CN-118530502-A Skin material for carrier and carrier ornament comprising skin material 延锋国际汽车技术有限公司 2024-08-23 CN claimed
CN-118528621-A Recyclable skin for a vehicle interior and vehicle interior component comprising the same 延锋国际汽车技术有限公司 2024-08-23 CN claimed
EP-2598560-A2 A POLYMERIC SUBSTRATE HAVING A GLASS-LIKE SURFACE AND A CHIP MADE OF SAID POLYMERIC SUBSTRATE Sony Corporation (JP) 2013-06-05 EP claimed
WO-2012013361-A2 A POLYMERIC SUBSTRATE HAVING A GLASS-LIKE SURFACE AND A CHIP MADE OF SAID POLYMERIC SUBSTRATE SONY CORPORATION (JP) 2012-02-02 WO claimed
US-20260103128-A1 COMPONENT FOR VEHICLE INTERIOR YANFENG INTERNATIONAL AUTOMOTIVE TECH CO LTD (US) 2026-04-16 US disclosed
WO-2025092815-A1 SKIN MATERIAL FOR VEHICLE AND VEHICLE DECORATION COMPRISING SKIN MATERIAL 延锋国际汽车技术有限公司 2025-05-08 WO disclosed
WO-2024255824-A1 RECYCLABLE SKIN FOR INTERIOR OF VEHICLE AND VEHICLE INTERIOR COMPONENT COMPRISING SAME 延锋国际汽车技术有限公司 2024-12-19 WO disclosed
CN-119071952-A Skin with heating function, preparation method thereof and vehicle interior part comprising skin with heating function 延锋国际汽车技术有限公司 2024-12-03 CN disclosed
CN-118530502-A Skin material for carrier and carrier ornament comprising skin material 延锋国际汽车技术有限公司 2024-08-23 CN disclosed
CN-118528621-A Recyclable skin for a vehicle interior and vehicle interior component comprising the same 延锋国际汽车技术有限公司 2024-08-23 CN disclosed
EP-3894516-A1 PLASTIC-TO-OIL PLANT, ACCORDING CRACKING REACTOR, AND RELATED METHODS FOR CONVERTING PLASTIC WASTE INTO PETROCHEMICAL PRODUCTS Pruvia GmbH (DE) 2021-10-20 EP disclosed
US-5668224-A TETRAALKYL- OR TRIALKYLAMMONIUM END GROUPS BAYLOR UNIVERSITY 1997-09-16 US disclosed
WO-1996030327-A1 PROCESS FOR THE PRODUCTION OF AROMATIC CARBOXYLIC ACIDS EASTMAN CHEMICAL COMPANY (US) 1996-10-03 WO disclosed
US-5451643-A PROTECTIVE COATINGS FOR METALS OR GLASS BAYLOR UNIVERSITY (US) 1995-09-19 US disclosed
WO-1994020296-A1 POLY (ALKYLENE DICARBOXYLATES) AND SYNTHESES THEREOF BAYLOR UNIVERSITY (US) 1994-09-15 WO disclosed
EP-0373559-B1 Spherical, cellular silicone rubber microparticles and method for their preparation DOW CORNING TORAY SILICONE (JP) 1994-07-13 EP disclosed
EP-0444633-A2 Polyorganosiloxane-based elastomer powder and method for its preparation Dow Corning Toray Silicone Company, Limited (JP) 1991-09-04 EP disclosed
EP-0373559-A2 Spherical, cellular silicone rubber microparticles and method for their preparation Dow Corning Toray Silicone Company Ltd. (JP) 1990-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103128-A1 COMPONENT FOR VEHICLE INTERIOR VMA21, SMC4, SMCHD1 ALDH1A1 4279/4885SMN1; SMN2 123/4885SRD5A2 2491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.