Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212953 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL213665 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Sulfamide SCHEMBL4638211 | 0.82 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL27605211 | 0.82 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6265435 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL7933892 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL6265221 | 0.75 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL6264114 | 0.75 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL13437655 | 0.73 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5594597 | 0.72 | PTGS2 (0.81) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682143-A2 | COMBINATIONS COMPRISING AN HSP90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | Pharmacia Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005041879-A2 | COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | PHARMACIA CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |