Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213457 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL30355967 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3252361 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5694332 | 0.82 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL6281419 | 0.81 | PTGS2 (0.85) | PTGS2PTGS1 | |
| SCHEMBL21113571 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL6265221 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL27585016 | 0.79 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL5698570 | 0.79 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL5071006 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140192-A2 | USE OF A CYCLOOXYGENASE-2 INHIBITOR AND ONE OR MORE ANTINEOPLASTIC AGENTS FOR COMBINATION THERAPY IN NEOPLASIA | G.D. SEARLE & CO. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000038730-A2 | USE OF A CYCLOOXYGENASE-2 INHIBITOR AND ONE OR MORE ANTINEOPLASTIC AGENTS FOR COMBINATION THERAPY IN NEOPLASIA | G.D. SEARLE & CO. (US) | 2000-07-06 | — | — | WO | claimed |