Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580213 | 1.00 | CA2 (0.54) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL22612302 | 1.00 | CA2 (0.54) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL5711132 | 1.00 | CA2 (0.54) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL8799307 | 0.98 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL13539144 | 0.91 | CA2 (0.57) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL10964151 | 0.91 | CA2 (0.57) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL9397701 | 0.91 | CA2 (0.57) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL22612259 | 0.91 | CA2 (0.57) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL5698787 | 0.91 | CA2 (0.57) | CA2MAPK1GRIK1GRIK2GPR84 | |
| SCHEMBL1920046 | 0.91 | CA2 (0.64) | CA2MAPK1CA1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285652-B1 | Novel fatty acid analogues for the treatment of hypertension | THIA MEDICA AS (NO) | 2006-08-16 | — | — | EP | disclosed |
| EP-1284139-B1 | Novel fatty acid analogues for the treatment of fatty liver | THIA MEDICA AS (NO) | 2006-08-02 | — | — | EP | disclosed |
| EP-1075260-B1 | NOVEL FATTY ACID ANALOGUES FOR THE TREATMENT OF SECONDARY RESTENOSIS | THIA MEDICA AS (NO) | 2005-10-19 | — | — | EP | disclosed |
| EP-1075258-B1 | NOVEL FATTY ANALOGUES FOR THE TREATMENT OF OBESITY | THIA MEDICA AS (NO) | 2003-08-20 | — | — | EP | disclosed |
| EP-1075259-B1 | NOVEL FATTY ANALOGUES FOR THE TREATMENT OF DIABETES | THIA MEDICA AS (NO) | 2003-07-23 | — | — | EP | disclosed |
| EP-0401193-B1 | Rubber compositions having improved processability | MONSANTO EUROPE SA (BE) | 1996-09-18 | — | — | EP | disclosed |
| US-5023289-A | Alkylthioalkanoic acid flow control agent | MONSANTO EUROPE, S.A. (BE) | 1991-06-11 | — | — | US | disclosed |
| EP-0401193-A1 | Rubber compositions having improved processability | MONSANTO EUROPE S.A./N.V. (BE) | 1990-12-05 | — | — | EP | disclosed |