Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238722 | 0.90 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL11762892 | 0.85 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5698978 | 0.85 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL140135 | 0.84 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL105934 | 0.82 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL229899 | 0.81 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL7990755 | 0.80 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL29964835 | 0.78 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL15037 | 0.78 | — | — | |
| SCHEMBL5681395 | 0.78 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036834-B1 | ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL | NIPPON CATALYTIC CHEM IND (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-6372355-B1 | MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-1036834-A1 | ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL | Nippon Shokubai Co., Ltd. (JP) | 2000-09-20 | — | — | EP | disclosed |
| US-6037394-A | ACRYLIC RESIN, BENZOTRIAZOLE, SOLVENT, AND ALKOXYSILANE REACTION PRODUCT WITH SILYLATION AGENT; PROTECTIVE COATINGS, WEAR RESISTANCE, WEATHERPROOFING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-03-14 | — | — | US | disclosed |
| EP-0934987-A1 | Primer composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5025049-A | Organic copolymer containing alkoxysilylated monomer, polyalkyl (meth) acrylate, crosslinking agent and ultraviolet absorber | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-5021266-A | Silicon based protective coating | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4960809-A | CURABLE MIXTURE OF ALKOXYSILYL-CONTAINING ADDITION COPOLYMER AND AN AMIDATED POLYMER OF AN AMINE-CONTAINING ALKOXYSILANE AND SILYLATING AGENT; ADHESION TO SILICONE OVERCOATINGS AND POLYCARBONATE SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |